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HomeHealth articlesatypical skin lesionsWhat Is the Role of Diascopy in Diagnosing Vascular Lesions?

The Role of Diascopy in Vascular Lesions

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Diascopy has proven to be invaluable in the field of dermatology for the evaluation of skin lesions, particularly vascular lesions.

Written by

Dr. Vineetha. V

Medically reviewed by

Dr. V. Srikanth Reddy

Published At March 20, 2024
Reviewed AtMarch 20, 2024

Introduction:

Diascopy is a straightforward and useful method in dermatology, and is highly important for checking skin issues, especially those related to blood vessels. Vascular issues can cover a broad range of skin conditions, from harmless ones like hemangiomas to more complicated ones like port wine stains and purpura. This article explains how diascopy is used to evaluate these vascular issues, including its basic principles, methods, and its clinical applications.

What Is Diascopy?

Diascopy is a clinical technique commonly used in dermatology to assess skin lesions, particularly those with vascular involvement. The term diascopy’ is derived from the combination of two words: ‘diaphanous’ and ‘scopy,’ which essentially means ‘to see through.’ The fundamental principle of diascopy is to observe how the skin lesion responds to pressure and the effect of pressure on the underlying blood vessels. This technique is particularly useful in identifying and characterizing vascular lesions, such as hemangiomas, port wine stains, purpura, and telangiectasias. By observing the changes in color and assessing the response to pressure, healthcare professionals can make more accurate diagnoses and treatment decisions related to these skin conditions.

What Is the Principle Behind Diascopy?

The principle of diascopy revolves around observing how the skin lesion responds when it is subjected to pressure. When pressure is applied to the skin, blood within the vessels undergoes displacement. In lesions with vascular involvement, this can lead to a change in color or appearance, which is crucial for diagnosis. Two techniques used in diascopy include:

1. Glass Slide Diascopy: In this method, a glass slide or a glass rod is gently pressed onto the lesion. The transparent glass allows for the visualization of vascular changes within the lesion. Observing color changes, such as blanching or remaining unchanged, can aid in identifying the nature of the vascular lesion.

  • Modification: In sensitive areas like the oral cavity, using two glass slides instead of one can prevent the breakage of a single slide under pressure, which could otherwise cause harm to the mucous membrane

2. Finger Pressure Diascopy: This technique involves applying manual pressure with a finger on the lesion. The vascular response to pressure, such as blanching or persistent erythema, helps differentiate between various vascular lesions.

What Are the Common Indications for Diascopy?

The common indications for diascopy are mentioned below:

  • The performance of diascopy is crucial in assessing a colored lesion, aiding in the differentiation between vascular and nonvascular pigmented lesions.
  • It is employed to distinguish purpuric lesions (caused by blood extravasation) from erythema (caused by vasodilation). Erythema exhibits blanching under diascopy, whereas purpuras do not.
  • In the case of granulomatous lesions, diascopy allows for the observation of the true color of the lesion. Lupus vulgaris lesions display apple jelly nodules upon blanching.
  • It can help identify the glassy brown appearance characteristic of papules associated with sarcoidosis, tuberculosis, and other granulomatous lesions.
  • Prior to conducting any biopsy or excision of a pigmented lesion in the oral cavity or on the skin.
  • To prevent any intraoperative complications resulting from blood overflow in vascular lesions.
  • Effective in detecting vascular lesions linked to liver cirrhosis.

What Is the Role of Diascopy in Diagnosing Vascular Lesions?

Diascopy helps doctors figure out if redness in a skin lesion is caused by blood in tiny vessels (inflammatory or vascular issues) or if it is due to bleeding (like small red spots). To do this, they press a glass slide against the lesion to see if it pales or not. Bleeding spots will not change color, but issues related to inflammation or blood vessels will. Diascopy can also reveal sarcoid skin lesions, which turn a specific color resembling apple jelly when tested. Diascopy has several clinical applications in evaluating characteristics such as vascularity, type, activity, and other factors of vascular lesions.

  • Diascopy helps dermatologists distinguish between vascular lesions and other skin conditions by observing how the lesion responds to pressure. Vascular lesions typically blanch (lose color) when pressure is applied, while non-vascular lesions do not.
  • It is valuable for differentiating vascular lesions from hemorrhagic lesions, as hemorrhagic lesions typically do not blanch and show persistent discoloration.
  • It assists in determining the type of vascular lesion. For example, hemangiomas often blanch completely under diascopy, while port wine stains may partially blanch or not at all.
  • Diascopy can help assess the activity of vascular lesions. Active lesions, such as inflamed hemangiomas, tend to blanch less or may not blanch at all, while stable or regressing lesions typically blanch well.
  • In cases of purpura, where there is bleeding under the skin resulting in purple or red discoloration, diascopy can confirm the presence of blood extravasation. This helps in diagnosing purpuric conditions and differentiating them from other skin abnormalities.

Diascopy can also be applied to assess the presence of inflammation in skin disorders. Inflammatory skin conditions may display specific changes when subjected to pressure, aiding in diagnosis and treatment decisions. This test is not restricted to vascular lesions alone. It can be utilized to investigate a wide range of dermatological disorders, including eczema, psoriasis, and blistering disorders, where the presence or absence of vascular involvement can provide valuable diagnostic information.

What Are the Important Diascopy Findings in Common Vascular Lesions?

Some Important diascopy findings in common vascular lesions include:

  • Hemangiomas: These typically show complete blanching under diascopy, which means they lose their color when pressure is applied.
  • Port Wine Stains: These may show partial blanching or no blanching at all, indicating that the lesions do not lose their color when pressure is applied.
  • Purpura: These lesions do not blanch, and the discoloration remains even when pressure is applied.
  • Petechiae: Similar to purpura, these small red or purple spots do not blanch under diascopy.
  • Sarcoid Skin Lesions: These lesions may show an apple jelly color when tested with diascopy, aiding in their identification.

How Is Diascopy Performed?

Diascopy is a simple and uncomplicated procedure. It involves gently pressing a hard, see-through tool like a plastic spatula, a clean glass slide, or two microscopic slides onto the lesion's surface. This pressure makes the lesion temporarily turn pale. In some cases, a glass capsule with local anesthetic or a stiff plastic strip is used to push down on the lesion to see how the blood disperses within it, causing it to look pale. The tool is held against the lesion with gentle pressure for one to two minutes. During this time, the blanching or paling of the lesion's surface, which makes it blend with the surrounding healthy tissue, is a sign of a positive test. When the tool is removed, the lesion initially looks pale for a few seconds before gradually filling up again from its blood vessels. By adjusting the amount of pressure applied, one can observe the blood vessels blanching and refilling.

Conclusion:

Diascopy is a useful tool for dermatologists when they need to figure out what is going on with certain skin problems, especially ones related to blood vessels. They can do this by pressing on the skin and watching how the blood vessels underneath react. This helps them diagnose issues like hemangiomas, port wine stains, purpura, and telangiectasias more accurately. While it is not a perfect method, experienced doctors find it really helpful in their work, making it easier to take care of patients and decide on the best treatments. Diascopy aids in the diagnostic process, helping clinicians make informed decisions regarding the nature and management of vascular lesions.

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Dr. V. Srikanth Reddy
Dr. V. Srikanth Reddy

Dermatology

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