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Tubercular versus Typhoid Ulcer

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Tubercular and typhoid ulcers are two distinct types of skin ulcers caused by different bacteria and have varying symptoms and treatment options.

Medically reviewed by

Dr. Kaushal Bhavsar

Published At April 20, 2023
Reviewed AtApril 20, 2023

Introduction

Ulcers are open sores that can develop on the skin or mucous membranes of the body. They can be caused by a variety of factors, including infections, injuries, and certain medical conditions. Two types of ulcers that are caused by bacterial infections are tubercular ulcers and typhoid ulcers. While both conditions share some similarities, there are several key differences between the two.

What Are the Causes of Typhoid and Tubercular Ulcer?

Both the tubercular and typhoid ulcers have different causes.

  • Tubercular Ulcers: Tubercular ulcers are caused by infection with the bacterium Mycobacterium tuberculosis. The bacterium spreads through the air when an infected person coughs or sneezes. When another person inhales the bacteria, they can become infected. The bacteria then travel to the lungs, where they can cause tuberculosis. In some cases, the bacteria can also spread to other parts of the body, such as the skin, bones, and joints, leading to the development of tubercular ulcers.

Risk factors for tuberculosis include living or working in crowded or poorly ventilated conditions, having a weakened immune system, and being in close contact with someone who has active tuberculosis.

  • Typhoid Ulcers: Typhoid fever, which can lead to the development of typhoid ulcers, is caused by the bacterium Salmonella typhi. The bacterium is usually spread through contaminated food or water. When a person consumes food or water that is contaminated with the bacterium, the bacteria travel to the small intestine, where they can cause typhoid fever. In some cases, the bacteria can also spread to other parts of the body, such as the liver, spleen, and bone marrow, leading to the development of typhoid ulcers.

Risk factors for typhoid fever include living in areas with poor sanitation and hygiene, consuming contaminated food or water, and traveling to areas where typhoid fever is common.

What Are the Symptoms?

Tubercular Ulcer: Tubercular ulcers can spread through various means, including hematogenous spread, ingestion of infected sputum or direct spread from infected contiguous lymph nodes and fallopian tubes. The following are the symptoms:

  1. Low grade fever.

  2. Weight loss.

  3. Present, long standing abdominal pain.

  4. Chronic diarrhea.

  5. Ascites.

  6. Night sweats.

Typhoid Ulcer: Typhoid ulcer is transmitted through a fecal-oral route as a result of unsanitary conditions and poor hygiene. The following are the symptoms:

  1. Fever with chills or stepladder type of fever.

  2. Constipation is common but diarrhea is rare.

  3. Sudden onset of abdominal pain.

  4. Ascites unlikely to occur.

  5. Fatigue.

How to Diagnose Typhoid and Tubercular Ulcer?

The diagnosis of tubercular and typhoid ulcers involves different methods:

Tubercular Ulcers:

  • Skin Biopsy: A sample of the affected skin is removed and examined under a microscope.

  • Skin Culture: A sample of the affected skin is taken and grown in a laboratory to determine if the bacteria that causes tuberculosis is present.

  • Tuberculin Skin Test: A small amount of a substance called tuberculin is injected into the skin to test for an immune response.

Typhoid Ulcers:

  • Blood Culture: A sample of blood is taken and grown in a laboratory to determine if the bacteria that causes typhoid fever is present.

  • Stool Culture: A sample of stool is taken and grown in a laboratory to determine if the bacteria that causes typhoid fever is present.

  • Serology: A blood test is used to detect antibodies to the bacteria that causes typhoid fever.

What Is the Treatment of Tubercular and Typhoid Ulcers?

Below are the treatments for tubercular and typhoid ulcers:

  • Tubercular Ulcers: The treatment for tubercular ulcers involves a combination of antibiotics that are effective against the bacteria that causes tuberculosis. The antibiotics are usually taken for several months to ensure that the infection is fully treated. The specific antibiotics used and the duration of treatment depend on the severity and location of the infection. In addition to antibiotics, surgery may be necessary in some cases to remove infected tissue.

  • Typhoid Ulcers: The treatment for typhoid fever involves antibiotics that are effective against the bacteria that causes the disease. The antibiotics are usually taken for seven to 14 days, and the choice of antibiotic depends on the severity and location of the infection. In some cases, hospitalization may be necessary for intravenous antibiotics and supportive care. In addition to antibiotics, it is important to stay hydrated and rest during the recovery process.

How to Prevent It?

Prevention is also important for both conditions. Here are some ways to prevent tubercular and typhoid ulcers.

Prevention of Tubercular Ulcers:

  • Get vaccinated with the BCG vaccine, which provides protection against tuberculosis.

  • Practice good hygiene, such as washing hands regularly.

  • Avoid close contact with people who have active tuberculosis.

  • Ensure proper ventilation in living spaces.

Prevention of Typhoid Ulcers:

  • Get vaccinated against typhoid fever.

  • Practice good hygiene, such as washing hands regularly.

  • Avoid consuming contaminated food or water.

  • Ensure proper sanitation in living spaces.

What Are Some Common Differences Between Tubercular and Typhoid Ulcers?

  • Tubercular and typhoid ulcers are both types of skin ulcers that can develop as a result of infection with specific bacteria.

  • Tubercular ulcers are more common in developing countries, whereas typhoid fever is more common in areas with poor sanitation and hygiene.

  • In addition to the skin, tuberculosis can affect other parts of the body, such as the lungs, bones, and joints, whereas typhoid fever primarily affects the digestive system.

  • Both tubercular and typhoid ulcers can cause significant morbidity and mortality if left untreated, highlighting the importance of prompt diagnosis and treatment.

  • The treatment for both conditions involves antibiotics, but the specific antibiotics used and the duration of treatment may differ depending on the severity and location of the infection.

  • In addition to antibiotics, supportive care may be necessary to help manage symptoms and promote healing.

  • It is important to take preventative measures, such as practicing good hygiene and sanitation, getting vaccinated, and avoiding close contact with infected individuals, to reduce the risk of both conditions.

  • Early diagnosis and treatment are key to preventing the spread of both conditions to others. It is important to seek medical attention if you suspect you have been exposed to either bacteria or if you develop symptoms associated with these conditions.

Conclusion

In conclusion, tubercular and typhoid ulcers are two different types of skin ulcers caused by bacterial infections. Tubercular ulcers are caused by Mycobacterium tuberculosis, while typhoid ulcers are caused by Salmonella typhi. Both conditions have different risk factors, symptoms, diagnostic methods, and treatments. Prevention of both conditions involves good hygiene practices and vaccination. While both conditions share some similarities, such as being bacterial infections that can lead to skin ulcers, there are several key differences between the two that make their diagnosis and treatment distinct.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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