HomeAnswersHematologyadhdMy 7-year-old daughter is suffering from ADHD and CAE and is on medications, but her blood work is of concern. Please help.

Can ADHD and CAE medications cause deviation in blood investigations?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

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Published At July 25, 2023
Reviewed AtJuly 25, 2023

Patient's Query

Hello doctor,

I am concerned about my 7-year-old daughter's recent blood work. She is 50 inches tall and weighs 54 lbs. She is taking Vyvanse 20 mg for ADHD and Zarontin for CAE. She was put on Zarontin four months back. Recently she has not been sleeping well. She has developed swollen lymph nodes on her neck. One swollen lymph node has been there for a while, and she is due for an ultrasound of her neck soon. Her doctor performed some blood work yesterday, and some of the results make me wonder what is happening to her. Today she was sleepy for most of the day.

The numbers that have me the most concerned are:

My ANC (absolute Neutrophil count) is 1000 neutrophils per microliter of blood , WBC (White Blood Cell) is 2600 per microliter of blood, globulin is 1.9 g/L and monocyte is 19.0 %.. What can cause this drop? What can cause this deviation from the normal ranges? What causes a sudden decline in WBC count?

Thank you.

Hello,

Welcome to icliniq.com.

I have read your query, and I can understand your concern.

Your child is taking anti-epileptic medication and drugs for attention deficit hyperactivity syndrome. As per mentioned report, neutrophil count is low, and monocyte count is high. Neutropenia can be caused by anti-epileptic medication, but anti-epileptic medication need not be stopped immediately. Other causes for low WBC (white blood cell) count can be autoimmune disorders like SLE (systemic lupus erythematosus), chronic infections like malaria, gram-negative septicemia, typhoid, tuberculosis, or some viral infection like parvovirus B19 and EBV like virus (Epstein-Barr virus). As monocytosis is also present, an infective etiology might lead to bone marrow suppression temporarily, and the neutrophils count can become low. If the enlarged lymph node is large enough, then FNAC (Fine needle aspiration cytology) must be done. This investigation is beneficial to rule out whether infective or malignant etiology is present. Treatment can be provided based on the cause. I suggest you consult a pediatrician for an examination.

I hope my answer will help you.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri

Pathology

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