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Q. Kindly explain my NT scan and double marker blood test reports in detail.

Answered by
Dr. Jimesh H Mavani
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Dec 03, 2016 and last reviewed on: Jul 02, 2019

Hi doctor,

I am 12 weeks 5 days pregnant. I got my NT scan and double marker blood test results. NT value 1.1 mm, free b-hCG 1.52 MOM, PAPP-A 0.37 MOM, trisomy 21+NT risk 1:1132, trisomy 21 1:169, trisomy 13/18+NT. In urine culture, there is no significant growth observed after 48 hours. I am currently, All 9D in the morning, Ecosprin and Endogest SR 200 in the night.

Dr. Jimesh H Mavani

General Practitioner Obstetrics And Gynaecology
#

Hello,

Welcome to icliniq.com.

I have seen the report completely (attachment removed to protect patient identity).

Your report is normal and there is no need to worry. If you want a detailed explanation about the report, then here you go. There are some genetic syndromes, which are happening worldwide in which baby can be seriously handicapped physically, body function wise or mentally. Now you cannot diagnose any genetic disease directly without baby cell as it contains DNA. But, the procedure (amniocentesis) for obtaining baby cell itself is very risky and can even lead to abortion and also more costly.

So, we are doing a screening test to diagnose the high risk pregnancies that have a high risk of getting that genetically abnormal baby. For that we combine different parameters and compare it with a standardized data to come to a ratio for chance of current pregnancy having that genetic abnormality. The test is negative and positive; according to either it is below the cutoff value or above. 1:250 meaning, 250 pregnancies like you having a chance of only 1 positive for that genetic abnormal baby.

So, as your report is good in which it is negative for Down's syndrome (trisomy 21) and also for 18 and 13 (Patau and Edward syndrome). So, your pregnancy is normal and no need to worry. You have to do only one thing and that is to follow normal medicines and precautions. One more thing I have seen in your report is that the cervical length is 3.0 cm. It is somewhat borderline at 12 weeks of pregnancy. For that you need to take proper rest. Just increase the duration of your rest time and continue Progesterone (Endogest 200) two or three times a day.


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Thank you doctor,

We are feeling a bit relaxed now. However, we need clarification on the PAPP-A value. As the value is low, our doctor has asked us to take Exhep 40 mg injection on alternate days. Is it mandatory to take this injection?

Dr. Jimesh H Mavani

General Practitioner Obstetrics And Gynaecology
#

Hi,

Welcome back to icliniq.com.

According to me, Exhep (Enoxaparin) and PAPP-A (pregnancy-associated plasma protein A) value do not have any correlation.

  • Ecosprin (Aspirin) and Exhep, both are to decrease the clotting tendency of blood, so that blood can easily circulate through the uterus to the baby and have a good growth.
  • But in view of complications, we advise it in patients who have previously had two to three or more abortions. Otherwise, you can continue Ecosprin and no need to start Exhep.
  • But as I said, I do not know the entire history and I gave my best clarification. There are also different treatment protocols in between different gynecologists. So, better ask your doctor about it.

But, I do not think there is any correlation between PAPP-A and Exhep. But, if you have a tendency of hypertension in pregnancy, then also we sometime start Exhep.


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