My blood group is B positive. I am going to marry a person with B negative blood group. Is there any problem?
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I can understand your concern.
From history, I hope you are telling that you (male) is B positive and your fiance (female) is B negative.
It will not cause a problem in first pregnancy but in second pregnancy severe hemolytic disease of the newborn can occur. So, we have to prevent this sensitization when she will be pregnant.
So, just keep this in mind and in first pregnancy of your wife (she is having a negative group as per history), she should be given Rh(D) immunoglobulin injections in the antenatal period at 28 week of gestation.
In addition, before marriage, you both should be investigated for thalassemia minor status.
For further information consult a hematologist online --> https://www.icliniq.com/ask-a-doctor-online/hematologist
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