What does CBC and RBC anisopoikilocytosis indicate?

Question

Hello doctor,

This is my CBC report, and everything is normal except RBC. In it, RBC shows anisopoikilocytosis, predominantly microcytic hypochromic cells along with normocytic hypochromic cells and a few target cells.

WBC is within normal limits. Platelets are adequate. MCV (mean corpuscular volume): 72.0 fL, normal range 80 to 100 fL. MCH (mean corpuscular Hb): 18.6 pg, normal range 30 to 36 pg. MCHC (mean corpuscular Hb concentration): 30.0 g/dL, normal range 32 to 36 g/dL. I will attach the report.

Please suggest a cause and a solution for this.

Thank you.

Answer 1

Hello,

Welcome to icliniq.com.

Your report is suggestive of microcytic hypochromic anemia. Do not worry about that. It is a treatable condition. With the recovery of the hemoglobin level by tablet, your PS (peripheral smear) will revert to normal. It is not an alarming condition. But I suggest the following workup for you.

1. Serum ferritin estimation.

2. Serum transferrin saturation.

3 Serum FEP (free erythrocyte protoporphyrin).

4. Serum TIBC (total iron binding capacity).

These four investigations help rule out iron deficiency anemia.

5. HB (hemoglobin) electrophoresis.

This fifth investigation will rule out any hemoglobinopathy if present.

Kindly revert back with these reports so that I can guide you further.

Hope I have answered your question.

Thank you.