iCliniq logo

Ask a Doctor Online Now

HomeAnswersOphthalmology (Eye Care)dry amdAre there any promising drugs under trial for dry AMD?

Do you have any thoughts on promising drugs for dry AMD?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Asif Manzoor

Medically reviewed by

iCliniq medical review team

Published At December 21, 2016
Reviewed AtMarch 10, 2023

Patient's Query

Hello doctor,

I am 63 years old. I was diagnosed with dry intermediate AMD about five years back. The VA then was 20/25, and now it is 20/60. I am currently on AREDS. I am a non-smoker. I have excellent health otherwise. The Amsler is normal. The recent OCT showed no fluid. Do you have any thoughts on promising drugs like Fenretinide, statins, or others under trial or research?

Answered by Dr. Asif Manzoor

Hi,

Welcome to icliniq.com.

For dry AMD (age-related macular degeneration), the recommendations mostly include AREDS2 (Age-related Eye Disease studies 2) formulation. The other recommendations are quitting smoking (in case of smokers), controlling hypertension, lipid level, diabetes, and regular checking with an Amsler chart to pick early conversion of dry AMD into wet AMD. Your decrease in vision over five years may be due to lens changes or cataracts; you have not mentioned the cataract surgery done or not. If there is no fluid or change on Amsler, then AREDS and other preventive measures are enough. Trials are underway on Fenretinide as that decreases cytotoxins production in the retina. The other trials being done include Saffron 20 mg/day. The evidence suggests that it is neuroprotective but needs more research and authentic results. These are still under trial, and there are no recommendations available. More treatment options are available for wet AMD as it is a vision-threatening condition. There are intravitreal injections and lasers (PDT- photodynamic therapy) options.

I would advise you to stick with the current therapy of AREDS and keep testing with Amsler. Keep in touch with your eye doctor about any new modality introduced for dry AMD. He will inform you.

Probable diagnosis

Dry AMD.

Treatment plan

AREDS and keep testing with Amsler.

Preventive measures

Stop smoking, control BP, blood sugar and lipid level.

Patient's Query

Hi doctor,

Thank you for the reply.

Saffron seems interesting. I have not had cataract problems, but I forgot to mention that my right eye can only count fingers due to childhood trauma, corneal tear at the age of eight years. I wonder the step an ophthalmologist would take in my situation. I will discuss this with him soon.

Answered by Dr. Asif Manzoor

Hi,

Welcome back to icliniq.com.

It is unfortunate to hear about your second eye. So, your left eye will be considered the only eye and precious one. There will be RPE (retinal pigment epithelium) and atrophic changes in dry AMD. They can also decrease vision if the cataract is not significant. The swept-source OCT (optical coherence tomography) can better view the RPE layer. I hope that will be available at every eye clinic.

Patient's Query

Hi doctor,

Thank you. Have a happy year ahead.

Answered by Dr. Asif Manzoor

Hi,

Welcome back to icliniq.com.

Thank you. May God bless you with healthy and successful life in coming years. Best wishes.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Asif Manzoor
Dr. Asif Manzoor

Ophthalmology (Eye Care)

Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Ask your health query to a doctor online

Ophthalmology (Eye Care)

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy