Q. I have Crohn's disease for a long period. Will it cause ED and PE?

Answered by
Dr. Gokul Vignesh Kandaswamy
and medically reviewed by Dr. Vinodhini. J
This is a premium question & answer published on May 26, 2020 and last reviewed on: Aug 18, 2020

Hello doctor,

I am a 29-year-old male and I am diagnosed with Crohn's Disease before 11 years and was taking Immuran 150 mg/day, and diagnosed with Streptococcus after semen culture at the beginning of this year. My main concern is ED and PE but the testosterone level is within the normal range. I want to know whether my problem is urology or neurology?



Welcome to

You have mentioned ED (erectile dysfunction) and PE (premature ejaculation). No details of medications tried so far. Can you elaborate on this?

Testosterone only indicates sexual drive, which you have not mentioned as a problem. So that being normal rules out nothing. There are no tests for ED and PE specifically. History is key. Better to discuss in person.

Immunosuppressive medications do not generally cause ED or PE. You have not mentioned any reason or symptoms for checking semen culture. In the absence of any such factors these semen tests can simply be a contaminant. Even if you have prostatitis, it is not likely to cause ED or PE. No need to treat semen culture unless you are symptomatic or in other words it will not help.

Have you checked fasting glucose, lipids, and thyroid function? In the absence of any such symptoms this is likely to be psychogenic especially because of age.

Treatment plan:

Please check the blood tests as above.

Preventive measures:

Reassurance, correct the factors if abnormal in the mentioned tests.

Regarding follow up:

Need a face to face/audio conversation to understand the issues in more detail.

Thank you doctor,

I took Cialis 5 mg (1 month daily) and supplements like L-arginine, Maca root, Ginseng, etc., but it did not actually work. I cannot maintain erection right before penetration. I did a semen culture because of a UTI (cystitis) and frequent urination (>9 times/day), smell in urine, and painful ejaculation.



Welcome back to

Thanks for the update. That is a lot of symptoms described.

Cystitis in men is abnormal but streptococcus is not a urinary bug. So atypical organism in urine needs evaluation. We need to check your flow rate also.

Painful ejaculation can be due to infection. Is this something new? It can be due to some issues like a stone in ejaculatory duct, etc?

Crohn’s disease generally does not affect large bowel especially rectum. Do you have any large bowel symptoms? We need to analyze this to see whether the infections are due to bowel issues. Again all these will not cause ED or PE.

Did you have premature ejaculation all your life or is it something new? Losing erection before penetration, is it because of ED or due to premature ejaculation?

I would suggest to use Cialis 20 mg an hour before intercourse, not daily dose. It gives better blood levels during performance. Try this for six to eight doses. If it alone does not help, try it in combination with 5 mg daily dose. There are some condoms with topical anesthetic inside it. It will prolong ejaculation and will help in PE. If your wife can understand, try masters and Johnson techniques which helps in prolonging PE.

Tramadol or Dapoxetine are drugs used for PE. I will recommend not to use them until you have tried the rest.

The Probable causes:

Psychogenic ED, primary PE.

Probable diagnosis:

ED and PE.

Regarding follow up:

Please bear in mind these are very common problems and do not get too stressed. It has the biggest negative effect in young age ED.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Erectile Dysfunction in Diabetic Population

It has a large psychological component in a huge number of patients - depression, a common psychiatric condition, is much more commonly seen in diabetic men ... This causes a rise in the pressure within the urethra of the pen...   Read full

Nutritional Management of Children with Crohn’s Disease and Ulcerative Colitis

Avoid Food Sensitivities Many times, it is observed that the children suffering from inflammatory bowel diseases develop intolerances towards certain foods ...   Read full

Is erectile dysfunction related to my thyroid disease?

With regards to erectile dysfunction, the most common cause at this age would be psychogenic ... I feel a strong sexual urge but then there is that ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Tomato Fever - Causes, Symptoms, Diagnosis, Treatment, and Prevention
Tomato fever is an unidentified and fast-spreading type of viral infection seen in young children. Scroll down to know m...  Read more»
Histrionic Personality Disorder - Causes, Signs, Symptoms, Diagnosis and Treatment
Histrionic personality disorder causes variations in the thinking ability of a person. Read this article to know more.  Read more»
Nighttime Skin Routine for Clear Skin
A skin that gets all the attention during the day requires a chance to repair, rejuvenate and replenish from day damage ...  Read more»

Ask your health query to a doctor online?

Ask an Urologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.