iCliniq logo

Ask a Doctor Online Now

HomeAnswersHematologyhigh lymphocyte countPercentage of B cells is high. Is it leukemia?

Percentage of B cells is high. Is it leukemia?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At January 27, 2018
Reviewed AtJune 8, 2023

Patient's Query

Hello doctor,

Here are my immunohistochemical results of peripheral blood: Absolute lymphocyte count 5812/uL reference (1000 to 3300) with CD19 (B cells) 62% reference (3 to 20%), CD45 positive, CD10 positive, and CD5 negative. How do we know if it is leukemia or not? Doctors in our town cannot interpret the result. The percentage of B cells is highly abnormal. Please help.


Welcome to icliniq.com.

At the age of 55 years, if persistent lymphocytosis is seen, then CLL (chronic lymphocytic leukemia) should be ruled out. For that, monoclonality should be confirmed by flow cytometry investigation and need bone marrow study apart from a peripheral smear examination report if needed.

In CLL, usually, peripheral smear examination report shows smudge cells and more than 90 % lymphocytes. So, provide a peripheral smear examination report and bone marrow aspiration study report, and flow cytometry report if available.

The mentioned markers are of B cells, but CD5 is negative, so further workup is needed, as mentioned.

I hope this will help you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri


Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Ask your health query to a doctor online


*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy