Does injecting aloe vera gel into the urethra cause sexual exhaustion?

Hi doctor,

Around six years ago, I mistakenly injected aloe vera gel into my urethra for masturbation. The end consequence was that firstly the urethra got significantly bigger during erection. Secondly, I could attain climax more readily than before, and finally, I would leak a lot of pre-cum during arousal. I am unsure what caused this, but I wonder whether I dilated the ejaculatory ducts or the opening to the seminal vesicles. The urethra has been sore or raw, especially at the back towards the rectum. Urinating is not painful, but the bladder might be slightly irritated. But in the last two weeks, I have had a persistent sense of being drained of sexual energy. I am always exhausted as if I have had orgasms. It is the type of exhaustion I would expect if I had 5 to 10 orgasms daily. It is dreadful. In addition, I no longer feel much sexual energy accumulating near the glans.

Usually, following climax, a few days of relaxation would result in sexual vitality returning to the glans. Instead, I had three recent and particularly rough masturbation before the onset of these symptoms. Perhaps they harmed or irritated something? First, I pressed my fingers tightly into the perineum during orgasm to prevent normal rectal muscle contraction. The third was holding the shaft tightly. In this situation, the urethra was already distended (containing a greater residual amount of air than usual). Another point of clarification is that I do have systemic soft tissue issues. It includes rectal muscles. Please know that I am aware of systemic health concerns and I am just seeking a potential urologic explanation. Finally, what may be causing my continual sexual exhaustion and lack of sexual accumulation in the glans? I cannot think of an apparent reason for recent masturbation harm.

Maybe I aggravated the situation? Could back pressure from air or sperm have aggravated the situation? Perhaps distension of the prostate's tiny ducts or more ejaculatory duct or seminal vesicle distension? However, I would have anticipated such damage to aggravate the condition I already had (i.e., reaching orgasm easier and being overly sensitive in the glans). However, this is not my new symptom. The latest sign is that my energy is being depleted before it can produce any pleasant sensations of arousal. It is as if I am experiencing a continuous low-grade orgasmic energy leak, with all the tiredness but no pleasure or contractions and no arousal or intention.

What are your thoughts, and have you seen anything like this before? What sorts of investigations should be done, and what could they reveal? Is there a surgical role in this type of problem? What kind of local anti-inflammatory therapy (for example, DMSO irrigation and injections of steroids) are available? I sense that surgeries are more about opening up confined structures, but my issue is that something has been excessively enlarged. Also, following a first topical self-treatment with a combination of DMSO and magnesium chloride, I noticed an instant improvement in my sensation of energy depletion. Unfortunately, subsequent treatments did not seem to help anymore.

Hi doctor,

Thank you for the reply.

I believe I described it incorrectly. I did not inject any medication (i.e., with a needle). Instead, I instilled aloe vera gel into the urethra opening with a syringe. I never thought this would induce granuloma. Is it possible that the problem is chronic inflammation? Now I doubt if it has caused severe harm to the urethra because I did so many times intending to dilate the urethra. Could this, however, have harmed the ejaculatory duct? Or, conversely, is it due to recent masturbation causing more significant dilatation of something by inhibiting orgasm?

Hi doctor,

Thank you for the reply.

During ejaculation, I feel no stricture or discomfort. By "blocking," I meant I manually prevented orgasm by applying pressure with my hand. The purpose of the aloe vera instillation was not to relieve a stricture. It was only to explore how it felt. I believe it stretched everything out, irritating and increasing the leakage of pre-cum.

Hi doctor,

Thank you for the reply.

As previously stated, no pressure was applied to the glans to prevent ejaculation. Instead, it was applied to the perineum. I am still looking for feedback on how that could have affected things. Also, I am still curious about the method of having increased pre-cum during arousal and also quicker orgasm as a result of injecting aloe vera. What are the most probable affected parts? Is it the ejaculatory duct? What about the prostate? Is this anything that DMSO instillation might aid with in terms of anti-inflammation?