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Can I take opioids to manage Interstitial Cystitis flare?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I was diagnosed with IC over a year ago, and at first, the pain was manageable. Now, my flares have gotten worse, especially during my cycle. I have pelvic pain, back pain, and urethral pain, all of which are five times worse during periods.

I have been working with my urogynecologist on bladder instillation and my primary doctor for medications. My physician has given me Amitriptyline, Hyoscyamine, and Ibuprofen. None of this touches the pressure pain that I am having during my menstruation.

I have tried yoga, physical therapy, and lots of other non-medical treatments. When is the appropriate time to discuss using Opiates during this time of the month for flares? I know it is a sensitive subject, but I have tried all the alternative therapies.

This seems like the only logical step, and I know that doctors are too scared to prescribe opioids because of their side effects. As they are still expected to relieve pain, I would need a small amount to get me through my monthly cycle flares. Do pain management doctors see IC patients? I am a 33-year-old female, and I weigh 240 lbs.

I also have other gynecological issues, such as a history of fibroids. Some have been removed, with current ones growing. I would greatly appreciate any advice or help.

Answered by Dr. Penchilaprasad Kandikattu

Education:

MBBS

Professional Bio:

Dr. Penchilaprasad Kandikattu is a General Practitioner with 15 years of clinical experience. He pursued his MBBS from Dr. NTR University of Health Sciences, Andhra Pradesh, and MD in General Medicine from Rajiv Gandhi University of Health Sciences, Karnataka. He is specialized in treating acute and chronic illnesses and provides preventive care and health education to patients. Currently, he is working at Sri Sai Hospital, Mancherial, Telangana.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

I feel sorry about your health condition. Interstitial cystitis is a chronic bladder condition that causes recurring bouts of pain and pressure in the bladder and pelvic area, often accompanied by an urgent and frequent need to urinate. There is no exact cause for it.

Different theories are proposed, but the exact one is not known. I suggest you follow these instructions:

  1. Avoid caffeinated drinks and alcohol. Avoid citrus fruits and chemical irritants. Every individual responds differently to a treatment. NSAIDs (nonsteroidal anti-inflammatory drugs) may be useful to relieve pain.
  2. Along with that, Tramadol 50 mg, thrice a day after food, may alleviate pain.
  3. Regular exercise and yoga also relieve symptoms.
  4. Continue Amitriptyline to reduce pain.
  5. Cyclosporine and bladder instillation with normal saline or potassium-containing solutions may give relief.
  6. Still, if the symptoms do not improve, please consult with your urologist. He will examine and treat you accordingly.

Thank you.

Medically reviewed by Dr. Sneha Kannan
Published At September 3, 2020
Reviewed At October 14, 2025

Education:

MBBS

Professional Bio:

Dr. Penchilaprasad Kandikattu is a General Practitioner with 15 years of clinical experience. He pursued his MBBS from Dr. NTR University of Health Sciences, Andhra Pradesh, and MD in General Medicine from Rajiv Gandhi University of Health Sciences, Karnataka. He is specialized in treating acute and chronic illnesses and provides preventive care and health education to patients. Currently, he is working at Sri Sai Hospital, Mancherial, Telangana.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Sneha Kannan is a skilled Dental Surgeon with expertise in providing general dental care, including scaling, fillings, and preventive treatments. She does oral surgery procedures such as extractions and minor surgical interventions. She does procedures in restorative dentistry, including crowns, bridges, and dentures. She is an expert in doing endodontic treatments such as root canal therapy. She is well-versed in doing procedures in cosmetic dentistry, including teeth whitening and smile correction. She can provide pediatric dental care for children’s oral health and preventive treatments. She promotes oral hygiene awareness and preventive dental practices.  

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Penchilaprasad Kandikattu is a General Practitioner with 15 years of clinical experience. He pursued his MBBS from Dr. NTR University of Health Sciences, Andhra Pradesh, and MD in General Medicine from Rajiv Gandhi University of Health Sciences, Karnataka. He is specialized in treating acute and chronic illnesses and provides preventive care and health education to patients. Currently, he is working at Sri Sai Hospital, Mancherial, Telangana.

This doctor is not available for online consultations on the platform anymore.

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