My scan at 12weeks and 5days is positive for T21. What to do?

Hi doctor,

I had an NT scan and a double marker test at 12 weeks and five days of pregnancy.

The report is as follows. Maternal serum screen 2: Dual test. (CLIA). HCG, Free Beta 69.00 ng/mL equivalent to 1.81 Corr. MOM's. PAPP-A 1.40 mIU/mL equivalent to 0.36 Corr. MOM's. Disorder screen positive cut off Trisomy 21 (Down) 1:250 and Trisomy 18/13 1:100. Ultrasound data CRL 62.9mm, Gestational age by CRL 12 + 4, Gestation age on the day of serum taking 12 + 5, Nuchal Translucency 2.00mm, NT' Mom's 1.23Mom, Nasal Bone Present. Measured by a radiologist: Trisomy 21 Screening-Screen positive.

The calculated risk for Trisomy 21 (with nuchal translucency) is above the cutoff, which indicates an increased risk. After the result of the Trisomy 21 test (with NT) it is expected that among 156 women with the same data, there is one woman with trisomy 21 pregnancy and 155 women with not affected pregnancies.

The PAPP-A level is low. The calculated risk by PRISCA depends on the accuracy of the information provided by the referring physician.' I wanted to know about the risk if in the first-trimester screening window is positive. Please suggest.