What does a hole in the heart mean?

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Yes, there is patent ductus arteriosus that is shunting from left to right (attachment removed to protect patient identity). As it is large, go for its closure. Consult any pediatric cardiologist or even same doctors who have done echo may be doing the closure. Medicines cannot close this. If it is not closed now, then it may create problem later.

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Effects and symptoms will occur when shunt will reverse from right to left. It can be closed by the simple procedure like an angiogram (through an artery of the wrist or thigh).