Dr. Madhav Tiwari
General Surgery
The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.
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Patient's Query
Hi doctor,
I am concerned about taking antidepressants and PSSD. I took one pill the other day and did not notice any side effects. I have been able to get erections and orgasms. My biggest concern is penis shrinkage from PSSD. I am currently taking Zoloft. Could this be possible by taking one pill? My penis has been hurting the last couple of days, but I think it is because I have been so focused on the situation. The size of my penis does not look like it has been altered, but maybe it has been, maybe a little bit in girth. If that were the case, is it reversible? Let me know. Thanks.
Hello,
Welcome to icliniq.com.
I read your query and can understand your concern.
Let me assure you saying that a majority of patients who are on SSRIs (selective serotonin reuptake inhibitors) do not face any issues with their sexual function. Even if they do, it is easily treated with some dose modification or addition of PDE5 (phosphodiesterase type 5) inhibitors. Some of the symptoms which may happen due to SSRI use (in a small number of patients) are premature ejaculation, low sex drive, or weaker ejaculation. It does not have any effect on penis size or girth at all. The benefits of starting SSRIs should be weighed against their side effects, something which can be done with your psychiatrist.
Hope this helps.
Please let me know if I can be of any further help.
Patient's Query
Hello doctor,
Thank you so much for your reply.
I only bring up the concern of penis shrinkage because I see a number of people talking about it on the internet, mostly due to people who have PSSD. It looks like a very rare symptom, and it is just concerning because some people can develop PSSD even after a dose of an SSRI. I am probably overreacting, but my penis has been quite sore with a dull aching pain the last two days. No injury to it or anything, but maybe that could be due to me directing all my focus to it the last couple of days. And as far as penis shrinkage goes, could it be common for a 29-year-old man to experience it? I do not drink or smoke, I work out regularly, I am not overweight, and I am currently not taking any medications, just a lot of stress over stupid things like this. Probably too much information, but I masturbated three times yesterday within a span of hours due to all the anxiety around this just to test and see if I am okay. Could masturbating like that cause scar tissue and penis shrinkage? I am sorry for all these random questions. I just want to put all my worries to the side so I can get over it and move on with my life. Thank you.
Hello,
Welcome back to icliniq.com.
I understand your concern.
Please be assured that a single dose of SSRIs would not cause any harm. Neither should you be worried about your penis shrinking in size at your age. Masturbating also does not cause any penis shrinkage or scarring. The only thing masturbating can do is cause a frenular tear, but that too if you are extremely aggressive whilst doing it. I think you should not worry about this and put your mind to ease. If your penis is sore or hurting, I suggest you, please avoid masturbation for a few days and take a single dose of over-the-counter pain medication.
Hope this has answered your query.
Kind regards.
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General Surgery
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