My daughter is 20 years old. She has chronic urticaria for more than five years. She is suffering from eczema (pompholyx) in the palm and sole for four years. She has Intense and prolonged itching in the vesicles of pompholyx in the palm and sole with occasional pain disturbing sleep and study. These are reduced in winter. Eruption of vesicles are reduced slightly on medication. The complete blood count is normal except lymphocyte 49%, IgE- 512 IU/mL, thyroid function is normal as of last month's test report. She takes a Montek-LC tablet for ten days, Clobetasol Propionate with Neomycin ointment, and Beclomethasone with Gentamicin lotion for two months. In addition, she takes Clomipramine 10, Fluoxetine 40, and Propranolol 10 for obsessive-compulsive disorder. What should I do now for relief from itching? Can she take the COVID vaccine? Please guide me.