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Does Itching Disturb Your Regular Activities?

Written by
Dr. Vidhi Talati Joshi
and medically reviewed by iCliniq medical review team.

Published on Jul 15, 2015 and last reviewed on Oct 19, 2021   -  6 min read

Abstract

This article discusses in detail the diagnosis and management of severe itching.

Contents
Does Itching Disturb Your Regular Activities?

Introduction:

Nowadays, itching is a major problem or symptom of most allergic, systemic or fungal diseases. Four out of 10 people have had some type of itching problem of the skin in their routine life. Severe itching disturbs the day-to-day activities of a human being.

What Is Itching?

Who Are Most Likely to Get Affected?

What Is the Pathophysiology of Chronic Itching?

There are many factors that trigger itching.

Keratinocytes:

Mast Cells:

Eosinophils:

What Is the Etiology for Chronic Itching?

Different diseases such as inflammatory skin diseases, metabolic diseases, liver and kidney diseases, lymphoproliferative diseases, and myeloproliferative diseases are the cause of severe itching.

Some dermatological causes of itching are:

The systemic diseases associated with itching are:

  1. Cholestasis of pregnancy.

  2. Primary biliary cirrhosis.

  3. Oral contraceptives.

  4. Hepatitis.

  5. Extrahepatic biliary obstruction.

  6. Drugs.

  1. Polycythemia vera.

  2. Multiple myeloma.

  3. Hodgkin’s disease.

  4. Iron deficiency anemia.

  5. Mastocytosis.

  1. Hypothyroid.

  2. Thyrotoxicosis.

  3. Carcinoid.

  1. Asthma.

How Is Severe Itching Diagnosed?

How Is Severe Itching Treated?

Precautionary Measures:

Local Approach:

Treatment should be established for the underlying cause of severe itching.

Systemic Approach:

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Last reviewed at:
19 Oct 2021  -  6 min read

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