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What is the dosage of Dapoxetine for premature ejaculation?

The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Ajay Singh

Medically reviewed by

iCliniq medical review team

Published At August 29, 2018
Reviewed AtSeptember 16, 2023

Patient's Query

Hello doctor,

I am 45 years and suffering from severe premature ejaculation (cannot sustain for a minute or two) and mild to moderate erectile dysfunction (less hardness and short length after erection, difficult penetrating other than the missionary position, long delay in repeat erection) since the beginning of my sexual life. For last few years, I am taking Dapoxetine 30 mg (Duralast 30) before sex. It gives me a bit control but as I find 30 mg not much effective so I started taking two pills of 30 mg sometimes together and sometimes after a gap of 3 to 6 hours. Occasionally, I also add 25 mg Sildenafil or Tadalafil 20 mg (Tazzle) for improving erection. My problems are as under:

  1. I find Dapoxetine 30 mg not effective but when I take two tablets, can control the ejaculation in a better way but has nausea feeling and low libido. I also feel too hungry after 1 to 2 hours of taking tablets. Besides even two tablets has effect for 2 to 3 hours and does not remain effective if sex is delayed. Now I started giving a gap of 2 to 3 hours between two doses of 30 mg which reduced the side effects. Is this pattern of dose fine?
  2. Is there a probability of any longterm effect of taking 60 mg daily dose of Dapoxetine?
  3. As most of the time one cannot fix the time of sex in advance as it depend upon the mood of the partner too. So Dapoxetinecannot be used as a curative medicine to improve the condition permanently or it is only SOS?
  4. How can I reduce the side effect especially of low libido and nausea?
  5. Effect of sildenafil remain a bit longer and help in erection even for two days of taking the tablet. What is your recommendation of doses? How to enhance the length of the penis as my penis face difficulty in reaching partner’s G spot and it reaches to full length only just before erection. Please advise a remedy.

Answered by Dr. Ajay Singh

Hello,

Welcome to icliniq.com.

I will answer as per order of your queries:

  1. Instead of taking two doses of 30 mg of Dapoxetine after a gap, take a single dose of 60 mg of Dapoxetine 20 minutes prior to intercourse. It will help.
  2. Dapoxetine is basically indicated for situational use only and not for daily use. Instead, you can take Paroxetine 20 mg daily at night which is indicated for PME as regular intake medication.
  3. For curative purpose start taking Paroxetine 20 mg at night daily. Also, you can use long delaying gel or condoms for this purpose also.
  4. Low libido and nausea can be treated by taking a combination of Shilajit and Ashwagandha and Pantoprazole and Domperidone capsules.
  5. You can take Sildenafil 50 mg on a situational basis (prior to sex) and not to take more than two tablets of Sildenafil in a week. Unfortunately, there is no capsule or oil available to increase the length of the penis.

For more information, consult a sexologist online --> https://www.icliniq.com/ask-a-doctor-online/sexologist

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Ajay Singh
Dr. Ajay Singh

Psychiatry

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