Patient's Query
Hi doctor,
I am 62 and have been on active surveillance for the last two years. My initial prostate biopsy was two years ago and showed one out of 10 needles cancerous, Gleason 6, slow growing and Prolaris test showing a medium growth rate. I had a second biopsy six months ago. Before the second biopsy, my PSA was 5 and four months after the second biopsy, my PSA was 16. My doctor recommended an MRI based on the elevated PSA.
An MRI was done two weeks ago. Prostate volume 81 cc, and two lesions were found. First lesion measuring 0.27 x 0.23 x 0.27 inch, Pi Rads 4, well contained mid gland and the second lesion 0.47 x 0.23 x 0.27 inch, ungraded, margins not sharply defined and a slight bowing of the capsule. I have had intermittent infections after the second biopsy and have been on a three-regimen of antibiotics. I have also experienced retrograde ejaculation after the second biopsy. I am thinking that the second biopsy caused my elevated PSA (5 to 16), swelling of my prostate and perhaps I can remain on active surveillance with antibiotics since the MRI showed my cancer being well contained. I am wondering if I should have surgery as recommended by my urologist to remove my prostate.
Kindly guide.
Hi,
Welcome to icliniq.com.
I have gone through your details. My main concern is the rise of PSA (prostate-specific antigen) from 5 to 16. However, it might be due to infection, since three months ago you have been taking treatment for infections. So, your PSA should have reduced if the rise was due to infection. At present, you are in the best stage and shape to get rid of cancer by radical prostatectomy. I suggest that you should undergo surgery and get rid of it. Also, you are only 62 years old. Since life expectancy is longer at some stage, you have to get rid of it before it progresses further. So, I suggest you do it now rather than later or too late.
I hope this information helps you.
Feel free to ask further queries.
Thank you.
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Answered byDr. Khant Shahil Rameshbhai
Medically reviewed byiCliniq medical review team
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