Q. Can Quetiapine make a person drowsy?

Answered by
Dr. Nidhi Jain
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jun 01, 2018 and last reviewed on: Oct 09, 2018

Hi doctor,

Two years ago, I was diagnosed with anxiety and depression and was treated with Fluoxetine, Zepam and Modafinil. Since one and a half years, I have been taking tablet Quetiapine 25 mg and tablet Lithoril 400 mg twice a day. Also, I am taking tablet Prodep 10 mg once in the morning for depression and border line personality disorder. During that period, I was even administered CBT. But, sometimes I get anxious and also depressed. My profession is teaching at the graduation level and I was clearly admired by my students. I teach with great enthusiasm, never get angry or show any reckless behavior and treat everyone with respect. After knowing my problem my wife left me. In the beginning, I did get a little frightened, but moved on with time and believe in living my life to the fullest. I exercise daily for 1 hour. I have been a scholar since childhood and was very excited. The tablet Quetiapine 25 mg is making me feel very drowsy as a result of which I sleep for about 9 hours a day. Initially, I thought it was because of depression. But, now I do not feel so. I am not sure whether I have borderline personality disorder or not. Am I taking right medication? Should I continue with the same? I do not want to get trapped. It would be of great help. Because, even to this day psychiatric issues are considered a taboo in our society. Thank you in advance.



Welcome to

  • Surely, psychiatric issues are a taboo these days. But, in my opinion you should continue with your medications according to the way it is responding in your body.
  • If the above medications are working well for you by keeping your mood pleasant and the interpersonal relationship positive then you should continue.
  • You can decrease the dosage gradually one by one or continue with the same dosage if any symptoms recur.
  • Generally in depression case, duration of a medicine depends on certain criteria such as the duration of illness, severity, family history and other medical conditions.
  • In your case, if it happens to be your first episode and it does not come along with any positive family history or any other medical conditions, then you can think of gradually decreasing or stop the medication. But, I will inform you in prior itself that there are high chances of recurrence when it is a case of mental illness.
  • Tablet Quetiapine is a good antipsychotic; tablet Lithoril (lithium) is a good mood stabilizer and tablet Prodep (Fluoxetine) is a good antidepressant as well as it has good anti-obsessional quality.
  • Though you are taking tablet Quetiapine in low dose and still you feel that it makes you drowsy, you can stop that and take tablet Lamotrigine 25 mg during night. This tablet will not get you drowsy and also help you in overcoming your sedation episodes.

For further information consult a psychiatrist online -->

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