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Do ESR and CRP levels rise with rheumatoid arthritis?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

My primary care physician said that I might have RA. My ESR rate was 27, my CRP was 14.1, and my CCP antibody IgG was 500. What does this mean? I have heard a high CCP result could indicate more aggression in my RA if that is what I have.

Hello,

Welcome to icliniq.com.

Yes, the chances of having RA (rheumatoid arthritis) or developing it are high. Anti-CCP antibodies are associated with RA and may also indicate an aggressive disease. However, there are various prognostic markers. This is only one of them. A high ESR and CRP and an increased number of swollen and tender joints are the other indicators. However, a good prognosis is associated with the early detection and treatment of this disease. I am sure you will be referred to a rheumatologist, who can start you on the appropriate treatment.

I hope that answers your query.

Regards.

Patient's Query

Hi doctor,

I have an appointment with a rheumatologist late next month. Getting one out here is tough. Is there anything I can do to be more comfortable until I get to see the rheumatologist?

Hello,

Welcome back to icliniq.com.

You can continue with Prednisolone for relief. You can do gentle exercises for your joints. Stay away from cigarette smoking. Symptomatic measures like hot fermentation and pain gels can help. Physiotherapy may also help.

Regards.

Medically reviewed byDr. Sowmiya D

Published At June 30, 2017
Reviewed AtMay 14, 2025

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