Dr. Goswami Parth Rajendragiri
Pathology
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Patient's Query
Hello doctor,
I am a 19-year-old boy with a thalassemia major, and I entered puberty just a few years ago. Lately, my hemoglobin levels have been consistently falling below 5 g/dl. I am currently taking Hydroxyurea medication, and I have noticed that my spleen is enlarged. Now, I have to make a decision whether I should consider undergoing a splenectomy due to the increased need for transfusions, or should I wait as during puberty and growth, the body's blood usage can increase. Please help and suggest the best course of action.
Hello,
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I understood your concern and will definitely help you regarding the issue. In thalassemia cases, if hypersplenism occurs and leads to an increase in blood transfusion requirements, splenectomy may be considered. This is because hypersplenism can lead to recurring anemia, neutropenia, and thrombocytopenia. However, the decision to undergo splenectomy involves various clinical considerations such as symptoms, the need for blood transfusion, and whether chelation therapy is ongoing. In some cases, if transfusion requirements increase but chelation therapy effectively manages the condition without significant clinical deterioration, splenectomy may not be performed. I suggest you consult a specialist, and discuss with them whether a splenectomy is needed based on the examination findings and reports.
I hope this has helped you. Kindly follow up if you have more doubts.
Thank you.
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Pathology
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