Patient's Query
Hi doctor,
I have nerve pain, fasciculations, and headaches. I am currently on Lisinopril 20, Amlodipine 5, Paxil 20, and Remeron 15. My blood report shows that I have a dsDNA antibody.
Kindly help.
Hi,
Welcome to icliniq.com.
Anti-dsDNA positivity implies that it is probably lupus. I suppose you have positive ANA (antinuclear antibody). Now, I need the following answers:
1. I need a detailed history of your symptoms.
2. Do you have any oral ulcers?
3. Do you have any photosensitive rashes on your face?
4. Do you have any joint pains?
Revert with the asked details for better help.
Thank you.
Patient's Query
Hello doctor,
I have muscle twitches and there are no oral ulcers or rashes on my face. Also, I do not have any carpal tunnel-like symptoms. My ANA test report is negative.
Kindly help.
Hi,
Welcome back to icliniq.com.
In this case, you do not need intensive treatment.
Please discuss with your doctor to prescribe you Hydroxychloroquine as it helps limit the further complications of lupus.
You can also ask for Levocarnitine, Calcium, and Vitamin D3.
I hope it helps.
If you have any further queries, please ask me.
Thank you.
Patient's Query
Thank you, doctor, for your quick reply.
So you mean this is lupus?
Kindly help.
Hi,
Welcome back to icliniq.com.
Theoretically, positive Anti-dsDNA means lupus. But we need to see other symptoms too. ANA can be a false positive, but Anti-dsDNA is usually not.
If there are no symptoms, then no need to treat it intensively. So the best is to take Hydroxychloroquine because no intensive treatment is warranted.
Thank you.
Patient's Query
Thank you, doctor, for your reply.
So do I get a lupus diagnosis, or are we just treating the Anti-dsDNA?
Kindly help.
Hi,
Welcome back to icliniq.com.
Anti-dsDNA is one of the diagnostic criteria of lupus. It is not that everyone with lupus will have all the symptoms. So, I would say you have lupus, but that does not require intense treatment. Now, you would also need a few more investigations related to it that includes mainly kidney function test, urine routine and microscopy. If that is fine, you would need Hcqs (Hydroxychloroquine) only, which would slow down the progression of disease.
Thank you.
Patient's Query
Thank you, doctor,
My Rheumatologist will not make a diagnosis. My other tests were normal. Could it possibly be anything else?
Kindly help.
Hello,
Welcome back to icliniq.com.
No, Anti-dsDNA is highly suggestive of lupus. But, whether it requires treatment or not completely depend on other system involvements.
Thank you.
Was this conversation helpful?
Answered byDr. Anshul Varshney
Medically reviewed byDr. Preetha. J
Same symptoms don't mean you have the same problem. Consult a doctor now!
Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.