I have urinary tract infection and Septra did not help. Kindly help.

Q. I have urinary tract infection and Septra did not cure my condition. Please suggest a better medication.

Answered by
Dr. Ankush Jairath
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Mar 26, 2022 and last reviewed on: Aug 20, 2023

Hello doctor,

I want to know the next steps I need to take for a UTI that has been treated with Septra that did not work, and then with Ceftriaxone IV followed by 400 mg of Norfloxacin BID. With both medications, I saw an initial improvement for 24 hours. Unfortunately, urine culture was not performed with the initial antibiotic. I had a culture done two days ago, but I do not have the results yet. My UTI symptoms are back, and I am concerned as I feel one of these antibiotics should have worked. I am currently on vacation. I will seek medical help in the morning again, but I wanted some direction or advice.

Kindly help.

Thank you.



Welcome to icliniq.com.

I read your query, and I can understand your concern. It would be best if you had culture-specific antibiotics. I would suggest starting empirical therapy comprising antibiotics, anti-inflammatory, and alpha-blockers. Tablet Levofloxacin 500 mg at bedtime for five days, syrup Citra Alka (Disodium Hydrogen Citrate) 10 mL three times a day for two weeks, tablet Chymoral Forte (Trypsin chymotrypsin) twice a day for five days, tablet Alfuzosin 10 mg at bedtime for a week, and tablet Pyridium (Phenazopyridine) one tablet thrice a day for 1 week (you will have orange color urine). Other than these, we might need symptomatic treatment if you have any other symptoms other than frequency, urgency and burning sensation. Do you have any fever? Do you have any history of diabetes or hypertension? Any ultrasound report?

Thanks and regards.

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