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Intravenous Iron Infusion - Significance and Test Procedures

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When the body's natural iron levels are depleted, an iron infusion can help. Read to learn more about the procedure.

Medically reviewed by

Dr. Rajesh Gulati

Published At January 3, 2023
Reviewed AtJune 22, 2023

What Is an Intravenous Iron Infusion?

Iron infusion is a therapy in which iron is infused directly into the circulation through a vein. It is required in people with iron insufficiency, iron deficiency anemia, or chronic kidney dysfunction. Iron is a mineral found in the human body. If iron levels are not enough, the body will not be able to produce hemoglobin and may become anemic. Intravenous iron, which is injected into the vein through a needle to boost iron and hemoglobin levels in the body, is one method of treating anemia.

Hemoglobin is a component of red blood cells that aids in the transport of oxygen throughout the body. If a person does not have enough hemoglobin, they may have fatigue, a fast pulse, and trouble breathing. An iron infusion may be administered when supplements fail to help someone with iron deficiency.

When oral iron supplementation fails to restore iron and hemoglobin levels in the blood effectively, IV (intravenous) iron infusions are advised. Because iron may be supplied quickly rather than gradually over time, the intravenous technique provides a quick and effective manner of distributing iron throughout the body. If patients are unable to take iron orally, are unable to absorb iron effectively through the stomach, or are unable to absorb enough iron owing to blood loss, they may require an IV infusion. Iron levels must be quickly increased to avoid medical issues or a blood transfusion.

Who Needs Iron Supplements?

Some people have lower iron levels in their blood than others. Among these groupings are:

  • People who have lost a substantial amount of blood due to cancer, ulcers, or heavy periods.

  • People who consume an iron-deficient diet.

  • People who use medications that interfere with the body's capacity to utilize iron to produce hemoglobin. Aspirin, Heparin, and Coumadin are examples.

  • People who are suffering from iron-depleting conditions, such as renal failure or pregnancy.

Because various medical conditions can cause low iron levels, a physician will also examine the patient's blood for the kinds of the iron present to confirm that a lack of iron causes anemia. If this is the case, the disease is known as iron-deficiency anemia.

Suppose a patient's blood counts have become so low that consuming iron supplements or boosting their regular consumption of iron-containing foods would be futile or too slow. In that case, an iron infusion may be administered. Some patients, such as those with inflammatory bowel disease, may benefit from an iron infusion since they cannot take an oral iron supplement.

How to Prepare for an Intravenous Iron Infusion?

An iron infusion might take up to three to four hours to complete. Depending on the degree of therapy required, the injection may take a bit longer in some circumstances. However, the modest infusion rate aids in the prevention of problems. Some simple things patients can do to prepare for an infusion include:

  • There is no need to fast for an iron infusion, so eat a regular breakfast and lunch.

  • Take their usual medicines, and prepare to have a tiny IV drip inserted into their arm or hand.

What Happens During an Iron Infusion?

  • Iron infusions are often administered at a hospital or hemodialysis center.

  • First, a doctor will use a needle, or another healthcare provider will introduce a tiny tube into a vein. This little tube is called a catheter. It is often injected into a vein, mainly in the arm or hand. The healthcare practitioner will then remove the needle, leaving the catheter in the vein.

  • The catheter is hooked to a long tube connected to an iron IV bag. A saline solution was used to dilute the iron. This solution is either pushed into the vein or drips down the tube and into the vein over time.

  • Several IV iron preparations are available, with Ferric Carboxymaltose being the most widely utilized these days (Ferinject). It is the most recent addition to IV iron, and the primary benefit is a substantially shorter infusion time of no more than 15 minutes. It is also linked to a decreased chance of an allergic response.

  • Patients may feel a tiny pinch when the IV needle is put in the skin. It is because, during the process, there may be some pressure at the insertion site.

  • The doctor administering the treatment will first provide a test dosage to verify that patients have no bad reactions to the iron. If seen, then the treatment will be halted.

What Are the Hazards and Side Effects of Intravenous Iron Infusion?

Individuals can resume their routine activities immediately following the injection. Patients may have some adverse effects immediately following the treatment. The majority of them are gentle. These are some instances:

  • Transient alterations in the taste of food and beverages.

  • Headaches.

  • Nausea and vomiting, as well as muscular and joint discomfort.

  • Breathing difficulty.

  • Constipation.

  • Dizziness.

  • Loose bowel motions.

  • Swelling.

  • Itching and rash, as well as a rise or reduction in blood pressure or heart rate.

  • A burning feeling or swelling at the injection location.

Severe hypotension (low blood pressure), consciousness loss, and collapsing are less common adverse effects.

In some cases, an anaphylactic shock may occur following an iron infusion. This severe allergic response can involve breathing difficulties, rashes, and intense itching. Anaphylactic shock needs immediate medical care.

Conclusion

Iron infusion is a faster therapy than supplements or dietary adjustments. An iron infusion is a rapid technique to boost the body's iron levels. It can be quite beneficial in cases of severe anemia. Iron infusions are an effective treatment for iron deficiency anemia. Iron infusions are not appropriate for everyone with low hemoglobin levels. Iron infusions, on the other hand, are one option for raising iron levels in those who cannot take or do not react to iron supplements.

Intravenous iron therapy is likely to be considered safe. While iron infusions pose hazards, improved formulations have helped lessen adverse effects.

Dr. Rajesh Gulati
Dr. Rajesh Gulati

Family Physician

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