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Dichloromethane Toxicity - Risks and Health Effects

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This article discusses dichloromethane toxicity, including sources, symptoms, treatment, and people at risk of poisoning. Read below to know more.

Written by

Dr. Vandana Rai

Medically reviewed by

Dr. Kaushal Bhavsar

Published At August 18, 2023
Reviewed AtAugust 18, 2023

Introduction

Dichloromethane, which is also referred to as methylene chloride, is a clear volatile solution with a sweet fragrance reminiscent of chloroform. It is frequently utilized as a solvent across several industries, including paint stripping, metal cleaning, and the production of pharmaceuticals and plastics. While it is a useful chemical, it can also be hazardous to human health. This article will discuss the potential dangers of dichloromethane toxicity and the effects it can have on the body.

What Is Dichloromethane Toxicity?

Dichloromethane toxicity occurs when an individual is exposed to this chemical in a way that causes harm to their body. This can happen through inhalation, ingestion, or skin contact. The toxicity of dichloromethane is due to its ability to break down into other chemicals, including carbon monoxide and formaldehyde, which can be harmful in their own right.

1. Inhalation

One of the most common methods by which individuals are exposed to dichloromethane is through inhalation. When the chemical is used in an enclosed space without proper ventilation, it can build up to dangerous levels. This can cause symptoms such as headache, dizziness, and nausea. Prolonged exposure to dichloromethane can lead to more serious effects, including liver and kidney damage and even death.

2. Ingestion

While less common than inhalation, ingestion of dichloromethane can also occur. This can happen when the chemical is accidentally swallowed or used in food processing or preparation. Ingestion of dichloromethane can cause symptoms such as abdominal pain, vomiting, and diarrhea. In extreme cases, it can lead to respiratory failure, coma, and death.

3. Skin Contact

Another way that individuals can be exposed to dichloromethane is through skin contact. This can happen when the chemical is used in cleaning products or when it comes into contact with the skin during the manufacturing process. Skin contact with dichloromethane can cause irritation, redness, and itching. Prolonged exposure can lead to more serious effects, including chemical burns and damage to the nervous system.

What are the Health Effects of Dichloromethane Toxicity?

The effects of dichloromethane toxicity can vary depending on the level and duration of exposure and the individual's age, health status, and other factors. Some of the most common effects of dichloromethane toxicity include:

1. Central Nervous System Effects

Dichloromethane is a central nervous system depressant that can slow down the brain's activity. This can lead to dizziness, confusion, and even unconsciousness. In severe cases, dichloromethane toxicity can cause seizures and coma.

2. Respiratory Effects

Inhaling dichloromethane can cause respiratory irritation, resulting in symptoms like coughing, wheezing, and breathing difficulties. Prolonged exposure can cause more serious respiratory problems, including bronchitis (inflammation of the bronchial tubes) and pneumonia (Inflammation of lungs).

3. Liver and Kidney Damage

Dichloromethane is metabolized in the liver, and prolonged exposure can cause damage to this organ. This can lead to symptoms such as abdominal pain, jaundice, and liver failure. In addition, dichloromethane can also cause damage to the kidneys, leading to kidney failure in severe cases.

4. Cancer

Exposure to dichloromethane has been linked to an elevated likelihood of developing specific cancer types, including liver, lung, and pancreatic cancer. This is due to the fact that dichloromethane can break down into other chemicals, some of which are known to be carcinogenic. Prolonged exposure to dichloromethane increases the risk of developing cancer, and this risk is higher for individuals who work in industries where they are regularly exposed to the chemical.

5. Reproductive Effects

Dichloromethane can also have negative effects on reproductive health. Exposure to the chemical for an extended period has been associated with decreased fertility in both males and females. In addition, exposure during pregnancy can lead to developmental problems in the fetus, including birth defects and low birth weight.

What Are the Sources of Exposure to Dichloromethane?

Dichloromethane is commonly used in various industries, which can lead to potential exposure for workers.

  • The chemical is often used as a solvent and paint stripper and is also used in the production of pharmaceuticals, plastics, and textiles.

  • Dichloromethane is also commonly used in dry cleaning and as a degreaser in metalworking.

  • People can be exposed to dichloromethane by inhaling the fumes or by coming into contact with the skin.

  • Household products, such as paint strippers, adhesive removers, and metal cleaners, may also contain dichloromethane, which can expose individuals at home.

Who Is At Risk of Dichloromethane Toxicity?

  • Workers in industries that use dichloromethane are at the greatest risk of exposure to the chemical.

  • Those who work in paint stripping, metal cleaning and degreasing, and chemical manufacturing are particularly at risk.

  • Workers in the pharmaceutical industry and those involved in food processing and preparation may also be exposed to dichloromethane.

  • Those who work in dry cleaning and laundry services may also be at risk of exposure.

  • Individuals who use household products containing dichloromethane may also be at risk of poisoning. These include individuals who use paint strippers, adhesive removers, and metal cleaners.

  • Certain medical conditions may also increase an individual's risk of dichloromethane poisoning. People with liver or kidney disease may be at higher risk of damage due to dichloromethane exposure, as these organs metabolize the chemical. Individuals with asthma or other respiratory conditions may also be more susceptible to respiratory irritation from inhalation of dichloromethane.

  • Pregnant women may also be at risk, as exposure to dichloromethane has been linked to fetal developmental problems.

How to Prevent Dichloromethane Toxicity?

Preventing dichloromethane toxicity requires a combination of workplace safety measures and personal protective equipment.

  • Employers who use dichloromethane should provide adequate ventilation to ensure that the chemical does not build up to dangerous levels in the workplace. Furthermore, it is important to train employees on the appropriate utilization and management of dichloromethane, which involves using personal protective gear like respirators, goggles, and gloves.

  • Individuals who use dichloromethane at home should also take precautions to avoid exposure. This includes using the chemical in a well-ventilated area, wearing gloves and goggles, and avoiding skin contact.

  • It is also important to follow the instructions on the label carefully, as misusing the chemical can increase the risk of exposure.

What Is the Treatment for Dichloromethane Toxicity?

The treatment for dichloromethane toxicity will depend on the severity of the exposure and the present symptoms. In cases of mild exposure, individuals may recover on their own without medical intervention. However, medical treatment may be necessary in moderate to severe exposure cases.

  • The first step in treating dichloromethane toxicity is to remove the affected individual from the exposure source and get them to fresh air.

  • If the exposure occurred through skin contact, the affected region should be cleansed meticulously using soap and water.

  • If the exposure is through inhalation, oxygen may be administered to help the individual breathe more easily.

  • In cases of severe exposure, hospitalization may be required. The affected individual may be given medication to help with symptoms such as seizures or respiratory distress. In some cases, the individual may need to be intubated to help them breathe.

  • If the exposure was due to ingestion, the individual should not induce vomiting, as this can cause further damage to the esophagus and stomach. Instead, they should seek medical attention immediately.

Conclusion

Dichloromethane is a useful chemical that is commonly used in various industries. However, it can also be hazardous to human health, causing a range of symptoms and long-term effects. The best way to prevent dichloromethane toxicity is through a combination of workplace safety measures and personal protective equipment. Employers and individuals who use dichloromethane should stay vigilant about the hazards and implement measures to minimize exposure. With proper precautions, it is possible to use dichloromethane safely and effectively while avoiding the harmful effects of toxicity.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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