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The Impact of Exercise on BDNF Levels: Understanding the Relationship

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Exercise is a crucial player in regulating BDNF levels and mood disorders. Read this article to know more.

Medically reviewed by

Dr. Kaushal Bhavsar

Published At April 1, 2024
Reviewed AtApril 1, 2024

Introduction

The role of exercise in achieving overall well-being cannot be emphasized enough. Regular exercise plays a pivotal role in regulating mental health. One of the most significant roles in this link is played by a known BDNF (brain-derived neurotrophic factor). This brain-derived protein plays a vital role in maintaining the nervous system. BDNF is essential for the development and maintenance of the synapses. Regular physical activity can cause this protein to be secreted optimally. This can, in turn, lead to a reduction in mental conditions and mood disorders.

What Is BDNF?

BDNF is a very important neurotrophin that helps in keeping the nervous system healthy. Neurotrophins are chemicals in the nervous system that help in its smooth functioning. It helps in promoting neuronal health, cognitive function, and synaptic functioning. BDNF is synthesized in various regions of the brain. However, it is found in higher concentrations in the hippocampus and cortex. It is crucial to maintaining the brain's plasticity and functioning smoothly.

What Is the Role of BDNF in Cognitive Functioning?

The brain's cognitive function includes various activities, such as problem-solving ability, memory, attention, and learning. The BDNF moderates the cognitive functions of the brain to a large extent. The right amount of BDNF needs to be secreted to maintain the optimum functioning of the brain. This is because BDNF maintains the synaptic joints and their plasticity. It prevents the synapses from weakening over time. This, in turn, helps maintain cognitive function.

What Is the Relationship Between BDNF and Exercise?

The relationship between BDNF and exercise aims to establish the relationship between mental health and exercise. Regular physical activity is the key to maintaining BDNF levels at optimal levels. Not only this, but regular exercise also aids in the overall well-being of neurological health.

The various aspects of exercises and their impact on BDNF include:

  • Aerobics and BDNF: Exercises like running, cycling, and jogging are aerobic exercises. Aerobic exercises are quite intense. They cause the heart rate to increase, pumping more blood into the body. This also causes more oxygen to flow through the body. People who perform aerobic exercises regularly tend to have an optimum level of BDNF. The blood flow and oxygenation in the body provide a conducive atmosphere for the secretion of this protein. This also lowers the risk of any neurodegenerative diseases.

  • Strength Training and BDNF: While discussing exercise, it is invariably aerobics. However, the recent spotlight that strength and resistance training are getting should be supported. Strength training includes activities such as weightlifting and bodyweight exercises. It has been observed that strength training also aids in maintaining BDNF levels. The pressure exerted on the muscles during strength training triggers certain factors that increase BDNF production. Hence, various types of exercises are beneficial in regulating this neurotrophin.

  • Duration and Intensity of the Exercise: The duration and intensity of the exercise play a vital role in determining the interplay between exercise and BDNF levels. It is observed that medium-intensity exercise is more effective than high-intensity exercise. High-intensity exercises tend to add stress-related reactions in the body, which can affect the release of BDNF from the body. Similarly, regular and long-term exercise tends to have more profound effects on the levels of BDNF. Exercise should be adopted as a lifestyle rather than a short-term solution to mental health issues.

What Is the Relationship Between Mood Regulation and BDNF?

BDNF plays a vital role in cognitive development, and its levels play an essential role in mood regulation. The BDNF levels influence mood disorders such as anxiety, depression, and bipolar disorder. Various studies have been undertaken to use BDNF as a therapeutic means to tackle mood disorders.

The multiple aspects of the BDNF and exercise relationship include:

  • Role in Alleviating Anxiety and Depression: It has been observed that individuals who have regular exercise habits have reduced expression of mood disorders such as depression and anxiety. The relationship between exercise and mental well-being is multi-dimensional. Exercise not only regulates BDNF levels but also stimulates the release of endorphins. Endorphins are the body’s natural feel-good hormones. Exercise can also act as a great stress reliever and sleep regulator. Both of which play an essential role in mood disorders.

  • Neuroprotective Effects of Exercise: The ambit of BDNF goes far beyond just mood disorders. This neurotrophin is very crucial in preventing neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, and prion disease. They protect the synapses and keep the nervous system in optimum working condition. In many cases with a genetic predisposition, BDNF can also delay the onset of such neurodegenerative conditions.

What Is Its Usage in Everyday Life?

Individuals can use the relationship between BDNF and exercise to maximize their cognitive and mental well-being.

The following are some ways in which this relationship can be maximized:

  • Making Exercise a Routine: One should exercise their daily routine to make the most of this neurotrophin. Exercise can include aerobic exercises, strength training, and yogic practices. This helps in keeping the BDNF levels at optimum.

  • Customizing Exercise Regimens Based on Personal Needs: When it comes to exercise, one size does not fit all. Hence, one should choose an exercise regime that suits them. Choosing an exercise can also be based on one’s personal choice. If a person chooses an exercise regime that they like, there are higher chances that they will stick to it.

  • Seeking Professional Guidance: Before diving into the complex world of exercise regimes, one can seek professional advice from fitness experts. This can help them approach their condition with a tailored approach. Exercise regimes can also be based on one’s likes and limitations.

Conclusion

The intricate interplay between exercise and BDNF levels gives a captivating narrative of how physical activity can positively influence brain health. The implications reach far beyond improved cognitive function, extending to mood regulation and potential neuroprotective effects. As the understanding of the intricate relationship between exercise and BDNF continues to evolve, one thing remains clear regular physical activity is beneficial for the body and a potent elixir for the brains, enhancing mental well-being and potentially safeguarding against neurological disorders.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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