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The Role of Omega-3 Fatty Acids in Preventing Heart Disease

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It has been demonstrated that omega-3 fatty acids dramatically lower the incidence of cardiac arrhythmia-related sudden death.

Written by

Dr. Palak Jain

Medically reviewed by

Dr. Yash Kathuria

Published At January 31, 2024
Reviewed AtJanuary 31, 2024

Introduction

Through a number of mechanisms, such as triglyceride (TG) lowering, membrane stabilization, and antithrombotic, anti-inflammatory, or antiarrhythmic properties, omega-3 fatty acids (FAs), such as eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids, may reduce the risk of atherosclerotic cardiovascular disease (ASCVD) events.

The capacity of omega-3s to decrease triglyceride levels is the most reliable indicator of their link with heart health. The body stores triglycerides, a kind of fat, in the blood. An increased risk of heart attack and stroke is associated with fatty build-up in the arterial walls, which has been related to high triglyceride levels.

What Is Omega-3 Fatty Acids?

Polyunsaturated fats, or omega-3 fatty acids, serve a number of vital purposes in the body. The quantity of omega-3s the body requires for survival cannot be produced. Therefore, omega-3 fatty acids are vital components. One important advantage is that it lowers triglycerides. Particular forms of omega-3s include ALA (found in plants), DHA, and EPA (found in seafood). Rich sources of omega-3s include flaxseed and chia seeds.

What Do Omega-3 Fatty Acids Do?

Omega-3 fatty acids support optimal bodily cell activity in every cell. They play a crucial role in shaping cell membranes and facilitating intercellular communication. Omega-3 fatty acids are essential to all cells, although they are particularly concentrated in the brain and ocular tissues.

Furthermore, the body uses omega-3 fatty acids as energy (calories) and maintains the health of several bodily systems. These consist of the endocrine and cardiovascular systems.

What Are the Benefits of Omega-3 Fatty Acids?

The heart health may benefit greatly from omega-3 fatty acids in numerous ways. Triglycerides are lowered, which is one of their main advantages. Hypertriglyceridemia, or having too many triglycerides in the blood, increases the risk of atherosclerosis and, therefore, causes blood vessel disease and stroke. Consequently, it is critical to maintain low triglycerides. Omega-3s may also be helpful since they reduce blood pressure and increase HDL cholesterol, which is healthy cholesterol.

According to some research, omega-3s may reduce the chance of:

  • Heart-related conditions (CVD).

  • Demise, in the event of CVD.

  • Unexpected death brought on by an irregular heartbeat (arrhythmia).

  • Prevent blood clots.

In addition to heart health, omega-3s may reduce the chance of developing:

  • Several cancer types exist, such as breast cancer.

  • Memory loss with Alzheimer's disease.

  • Macular degeneration brought on by age (AMD).

What Are the Best Food Sources of Omega-3 Fatty Acids?

The following are the best food sources of omega-3 fatty acids:

  • Nuts and seeds (walnuts, chia seeds, and flaxseed).

  • Plant oils (including canola, soybean, and flaxseed oils).

  • Seafoods.

  • Vegetables with green leaves.

  • Cereals, pasta, dairy, and other foods containing omega-3 fatty acids.

Numerous factors, including age and the sex allocated at birth, determine how much ALA one requires.

The following are general recommendations:

  • Male - 1.6 grams.

  • Female - 1.1 grams.

  • Pregnant women - 1.4 grams.

  • Breastfeeding mother -1.3 grams.

What Is the Role of Omega-3 Fatty Acids in Preventing Heart Disease?

1. Lower Triglyceride

The following are the heart health benefits of Omega-3 fatty acids in preventing heart disease:

The capacity of omega-3s to reduce triglyceride levels is the most reliable indicator of their association with heart health. One kind of fat that is present in the blood and is deposited as body fat is triglycerides. Elevated triglyceride levels have been connected to fatty accumulation in the arterial walls, hence raising the risk of stroke and heart attack.

2. Decreased Chance of Arrhythmia

Arrhythmia is the term used to describe an irregular heartbeat. While atrial fibrillation (AFib) and other arrhythmias are benign, they can raise the risk of stroke and other major heart problems. Although there is no effective medication to address issues with cardiac rhythm, some research has linked a higher consumption of omega-3s to a lower risk of arrhythmia.

3. Decreased Plaque Development Rate

Fat, cholesterol, and calcium are the main components of plaque, which can build up in the arteries and restrict the body's ability to pump oxygen-rich blood throughout it. There is a link between a diet high in seafood and a lower risk of stroke and heart attack. Omega-3 fats are abundant, whereas saturated fats are scarce in seafood. Although this has not yet been thoroughly demonstrated in clinical studies, consuming omega-3s may help prevent cardiovascular disease since they contain anti-oxidant and anti-inflammatory properties, as well as the potential to enhance the function of the endothelial cells that line blood arteries.

4. Reduced Blood Pressure

Heart attacks and strokes can result from elevated blood pressure. Omega-3 fatty acids have beneficial effects on blood pressure. It has been demonstrated that greater dosages of omega-3 fatty acids lower diastolic blood pressure, which measures the pressure in the arteries between heartbeats, and systolic blood pressure, which measures the pressure in the arteries during a heartbeat.

5. Lowering Inflammation

Heart attacks, strokes, and heart disease are all influenced by inflammation. It causes plaque, composed of fatty compounds, to form more quickly in blood arteries and become more loosened, which might result in blood clots. Supplements containing seafood have been shown to elevate the body's levels of anti-inflammatory molecules for as long as twenty-four hours; however, it remains unclear if this lowers the risk of heart disease.

Conclusion

Omega-3 fatty acids are generally beneficial to cardiovascular health through several possible methods. Healthy cholesterol, or high-density lipoprotein, is elevated by omega-3 fatty acids while triglyceride levels are lowered. Additionally, they could lessen platelet aggregation, which could stop the coronary arteries from clogging, which would impair or stop the heart's blood flow. Omega-3 fatty acids may reduce the likelihood that the heart may beat irregularly.

Through their impact on metabolism, omega-3 fatty acids may also lower inflammatory indicators in the body, improve artery compliance, and slow the onset of atherosclerosis. The activities of the heart, blood vessels, lungs, hormones, and immune system depend on omega-3 fatty acids, which are significant parts of cell membranes. According to research, eating seafood has been linked to heart health, especially if these items are selected over less healthful options. The chance of dying from heart disease can be decreased by eating seafood one to four times a week.

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Dr. Yash Kathuria
Dr. Yash Kathuria

Family Physician

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