Radical Cystectomy for Bladder Cancer: Risks, Benefits, and Recovery

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Radical cystectomy is a procedure performed to treat bladder cancer. It involves the complete removal of the bladder along with surrounding structures.

Medically reviewed by Dr. Manzoor Ahmad Parry
Published At December 28, 2022
Reviewed At April 22, 2026

Education:

BDS

Professional Bio:

Dr. Geetha Bhavani Gaddam is a skilled Dental Surgeon with expertise in preventive, restorative, and cosmetic dentistry. She is dedicated to providing compassionate, patient-centered care focused on oral health and creating confident smiles. Her areas of specialization include root canal treatments, dental restorations, smile design, and oral hygiene education, ensuring long-term dental wellness and a positive experience for every patient.

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Education:

DM

Professional Bio:

Dr. Manzoor Ahmad Parry is a Nephrologist specializing in kidney health, skilled in diagnosing and managing acute and chronic kidney diseases, hypertension related to kidney issues, electrolyte imbalances, dialysis management, and patient education for kidney disease prevention and long-term wellness.

This doctor is not available for online consultations on the platform anymore.

Table of Contents

What Is Radical Cystectomy?

Suppose you are confirmed with the diagnosis of bladder cancer that fails to respond to the traditional forms of bladder cancer treatments. In that case, your physician may suggest radical cystectomy (bladder removal surgery), which involves the complete removal of the bladder.

The procedure comprises two steps - radical cystectomy (RC) and urinary diversion. In radical cystectomy, your doctor will completely remove the bladder along with nearby lymph nodes. This helps to prevent the spread of cancer. While performing this procedure, the male reproductive structures, like the vas deferens and prostate, are removed. Certain organs that play a vital role in reproduction are removed in females.

Since the bladder is no longer present, the second stage is to create a way to store and eliminate the urine from our body. This could mean developing an opening in your abdomen called a stoma. Sometimes, a new bladder is created using the intestine, which is known as a neobladder. The radical cystectomy procedure is the gold-standard treatment for managing advanced bladder cancers. It is always combined with chemotherapy and lymph node removal. Less invasive techniques are now available due to recent advances in treatment procedures. These procedures provide a quicker recovery, but their long-term effectiveness is still being studied.

Who Needs a Radical Cystectomy?

A radical cystectomy is advised when you do not notice any improvement with other forms of treatment.

Here is when the doctor will advise you on this treatment -

  • Cancer that has spread to the muscular layer of the bladder.

  • If you are diagnosed with colon or prostate cancer, this procedure is performed to avoid metastasis.

  • Radical cystectomy is indicated when you are suffering from interstitial cystitis. The surgery is done only when all other traditional treatments have failed to treat it.

  • Any developmental defect in the bladder might require cystectomy.

  • Certain cases of transitional cell carcinoma of the bladder require radical cystectomy. It is more common in individuals with a bladder diverticulum, a condition in which there is a bulge in the bladder wall that resembles a pouch. Cancer or infection is common in the pouch.

  • The existence of a fistula that connects the colon and the bladder necessitates a cystectomy.

What Happens Before the Surgery?

An appointment with your doctor before the surgery generally involves discussing your overall health and the process involved in the surgery.

Here are a few things that typically happen before the procedure -

  • Your doctor checks vital signs to avoid any last-minute complications.

  • Your doctor will explain whether you will undergo partial or radical cystectomy.

  • Your doctor will evaluate your complete medical history.

  • Also, inform your doctor about your current medications, including over-the-counter medicines, herbal supplements, Aspirin, or any other blood thinners, because this may increase your risk of bleeding during surgery.

  • Inform your doctor if you are allergic to latex, iodine, or other medications.

This appointment is to ask questions, clarify doubts, and feel confident about the procedure. The better prepared you are, the easier everything will be.

What Happens During the Procedure?

You know what? You are not alone while undergoing the cystectomy procedure. You can expect a team of doctors around you. The team includes a urologist, an anesthesiologist, and nurses.

So, how is the radical cystectomy procedure done step-by-step? The initial step is to administer general anesthesia, which makes you not feel pain, and you will fall asleep. Then, the urologist will perform the surgery using one of two techniques.

  • Open Cystectomy: In this method, your surgeon will make a long vertical incision between your belly button and pelvic bone to remove the bladder. This is the traditional method. Due to longer incisions, it would take a long time to heal.

  • Minimally Invasive Surgery: In this approach, your surgeon will make four to five small incisions instead of one big incision. Your surgeon will insert small tools through the incision to work on your bladder. This is called laparoscopic surgery.

  • Robotic Surgery: During this procedure, your surgeon controls robotic tools to perform the surgery. The tools provide a clear vision and precise movements.

What Are the Types of Urinary Diversion After Surgery?

Even if your bladder is removed, you will need something to store and eliminate the urine from your body. Urinary diversion surgery is the solution for that!

Surgeons develop a unique way for urine to exit the body, with three major choices to consider:

  • Ileal Conduit: Consider this a simple urine-rerouting mechanism. Your surgeon connects a small part of your small intestine (known as the ileum) to your ureters, which are the tubes that deliver urine from the kidneys. The other end of the ileum exits your abdomen through a stoma and is connected to a bag to collect the urine.

  • Continuous Cutaneous Diversion: This is an improvised version of the ileal conduit. This method creates a small pouch using a larger portion of the intestine to collect and store urine. It is connected to the ureters and then to the stoma. Instead of connecting directly to the bag through the stoma, you can empty the pouch a few times a day using a catheter.

  • Neobladder: This is a more natural method than any other. In this, your doctor uses a portion of the intestine to create a new bladder and connect it to the urethra. Urine flows as before without needing a stoma, bag, or catheter. It may take some time to get control of this, but most people will get adjusted to it. This may not suit everyone, so check with your doctor to see if it is right for you.

What Happens After the Procedure?

Here is what happens after the surgery.

  • Your surgeon closes the cut on your abdomen using sutures. It is then covered with protective bandages.

  • The anesthesiologist will stop anesthetic medicine, and you will regain consciousness in some time.

  • You will be moved to a recovery room. You will be constantly monitored for your vital signs.

  • Is radical cystectomy painful? Oh yes, it is! A pain management specialist will help you manage pain with the help of medications or other strategies for pain relief.

How Long Does Recovery Take?

Bladder cystectomy recovery is not the same for all. It varies based on the type of surgery you have undergone and your overall health. It generally takes a few weeks or months to recover after surgery. If you have undergone partial cystectomy, your recovery period is less than that of those who have undergone radical cystectomy. In case of partial cystectomy, you will have to urinate often since the size of your bladder is reduced. In contrast, in radical cystectomy, you will have to adapt to using the external bag to eliminate urine.

What Are the Complications of Radical Cystectomy?

Radical cystectomy complications are:

  • A few may report blood clotting.

  • Infection is a common side effect reported by many individuals.

  • A few may go through some damage to the nearby structures.

  • You may get anesthesia-related complications.

  • Men may experience erectile dysfunction after the surgery.

  • Women may have difficulty with arousal due to nerve damage.

Conclusion:

Radical cystectomy is a procedure that helps treat bladder cancer. You will require a few months for recovery after surgery. If you notice any complications like bleeding, abnormal pain, nausea or vomiting, or any changes in your stoma during your recovery period, report to your doctor immediately. Your doctor will find the cause and help treat it to avoid further progression.

Keynote from iCliniq:

The process of complete removal of the bladder may be frightening, but you can overcome this with suitable support. The surgery is carried out by doctors from various specialties, including anesthesiologists, urologists, and nurses. Since it is a major surgery, you will require more time to heal after the surgery. If you have any concerns after the surgery, you can contact iCliniq doctors for expert advice.

Frequently Asked Questions

What Is the Difference Between Radical Cystectomy and Radiotherapy?

Muscle-invasive bladder cancer can be treated through the current standard of care by radical cystectomy (RC). Whereas bladder can be preserved through radical radiotherapy is nowadays done to gain interest in improving the quality of life and maintaining reasonable oncological outcomes.

How Is Radical Cystectomy Done Along With Ileal Conduit?

For urinary diversion, an ileal conduit is a well-described procedure that can be done after radical cystectomy. A short segment of the ileum allows the urine to pass through the abdominal wall and empty it through an everted stoma into a stoma collection device. 

How Is the Radical Cystectomy Procedure Done?

The radical cystectomy procedure on men and people assigned male at birth (AMAB) involves surgeons who always cut the vas deferens and remove the prostate and seminal vesicles. In women and people assigned female at birth (AFAB), surgeons remove the uterus, fallopian tubes, ovaries, and cervix.

How Is Radical Cystectomy Defined?

Radical cystectomy is defined as a procedure that removes the entire bladder. This procedure includes the removal of the prostate and seminal vesicles in men and the removal of the uterus, ovaries, fallopian tubes, and a part of the vagina in women.

How Much Time Does It Take To Complete Radical Cystectomy Surgery?

To complete radical cystectomy in people, surgeons usually take four to six hours.

Why Is Radical Cystectomy Defined as a Major Surgery?

Radical cystectomy, and surgical removal of the bladder, are defined as standard treatment care for patients with muscle-invasive bladder cancer. This radical cystectomy is defined as a major surgery because it has a significant risk of complications and potentially will lead to the individual's death.

Can Radical Cystectomy Surgery Be a Dangerous Surgery?

Surgeons generally recommend cystectomy to treat bladder cancer, which involves full or partial removal of the bladder in the individual. However, radical cystectomy surgery is dangerous because when surgeons remove the entire bladder, they provide a new way for urine to leave. And in turn, it includes risks like bleeding, infection, and sexual side effects.

Can a Radical Cystectomy Procedure Be Successful or Not?

Radical cystectomy combined with pelvic lymph nodes is the most effective treatment for muscle-invasive bladder cancer. A patient who underwent radical cystectomy shows five-year survival rates of 54.5 to 68 percent in studies conducted in Western countries.
Although radical cystectomy shows a high risk of morbidity, it is considered the best option to cure in a few patients.

What Is the Individual Survival Rate of Radical Cystectomy?

A patient who underwent radical cystectomy shows five-year survival rates of 54.5 to 68 percent in studies conducted in Western countries.
Characteristic Features                               Number of Cases in Percentage
Organ confined disease                                              212 (78.2)
Urinary diversion form of conduit                                  117 (43.2)
Neobladder                                                                       151

What Is the Classification of Non-invasive Bladder Cancer?

Urothelial carcinoma is subclassified into a heterogenous group called non-muscle invasive bladder cancer (NMIBC). A muscle-invasive disease is defined as a significant variation in individual risk of recurrence and progression.

Can Massive Invasive Bladder Cancer Be Curable?

Better survival rates are seen in muscle-invasive cancer patients when they are treated with chemotherapy before cystectomy. The standard care for patients with muscle-invasive bladder cancer can be done by combining preoperative chemotherapy and widely recognized surgery.

Can Chemotherapy Give to Muscle-Invasive Bladder Cancer?

Usually, chemotherapy can be given before or after the surgery in people with muscle-invasive bladder cancer. And also, they need to tolerate more aggressive treatment. The commonly used chemotherapy given to treat bladder cancer includes cisplatin and gemcitabine. Carboplatin and gemcitabine. Four drugs, methotrexate, vinblastine, doxorubicin, and cisplatin, are included under MVAC.

Does Non-muscle Invasive Bladder Cancer Show Metastasis?

Non-muscle invasive bladder cancer is rarely a metastatic disease having less than 10 percent of lymph node invasion. Based on the tumor stage, non-muscle invasive bladder cancer can be treated with local therapy, which includes transurethral resection of the bladder tumor and intravesical therapy.
Distant metastasis is diagnosed in two cases of NMIBC in the follow-up period after transurethral resection with either intravesical recurrence or progression to muscle-invasive disease.
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