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Ways Sleep Apnea Can Hurt the Health

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Sleep apnea is a prevalent sleep disorder characterized by interrupted breathing during sleep.

Medically reviewed by

Dr. Prakashkumar P Bhatt

Published At April 2, 2024
Reviewed AtApril 2, 2024

Introduction

Sleep is often undervalued, with many not paying attention to the importance of a good night's rest. One common yet underestimated sleep disorder is sleep apnea in which the breathing continuously stops and starts during sleep. Beyond the disruptive nature of snoring associated with sleep apnea, the disorder poses a more insidious threat to overall health.

What Is Sleep Apnea?

Sleep apnea is a sleep disorder characterized by repeated pauses in breathing during sleep. These pauses last for a few seconds to minutes and may occur many times throughout the night. The most common types of sleep apnea are obstructive sleep apnea (OSA), central sleep apnea, and complex sleep apnea syndrome.

  • Obstructive Sleep Apnea (OSA): This is the most prevalent form of sleep apnea. It causes a partial or complete airway blockage. As a result, breathing is momentarily interrupted or significantly reduced, leading to a drop in oxygen levels in the blood.

  • Central Sleep Apnea: Unlike OSA, central sleep apnea is unrelated to physical airway blockage. The lack of communication leads to a temporary cessation of respiratory effort.

  • Complex Sleep Apnea Syndrome: This type combines both obstructive and central sleep apnea and is also called treatment-emergent central sleep apnea. It may occur in individuals who initially had OSA but develop central sleep apnea when undergoing treatment with positive airway pressure (PAP) therapy.

How Does Sleep Apnea Hurt the Health of a Person?

Cardiovascular Complications: Sleep apnea's connection to cardiovascular health extends beyond its reputation as a nocturnal nuisance. The disorder's influence on the cardiovascular system is profound, with potential ramifications that stretch far into the waking hours.

  • Oxygen Deprivation and Stress Hormones: During sleep apnea episodes, the normal flow of oxygen is disrupted as breathing momentarily ceases. This intermittent hypoxia triggers a cascade of physiological responses. These hormones play a pivotal role in elevating blood pressure, contributing to a state of hypertension. The cumulative effect of recurrent apnea episodes can lead to a chronic increase in blood pressure.

  • The Hypertension Link: Hypertension, or high blood pressure, is a well-established risk factor for cardiovascular diseases. The sustained increase in blood pressure associated with untreated sleep apnea creates an environment conducive to the development of various heart-related issues. Individuals with sleep apnea may find themselves at an elevated risk of experiencing heart attacks, strokes, and other cardiovascular events. It's essential to recognize the interconnectedness of sleep apnea and hypertension to implement effective interventions that address both conditions.

  • Impact on Vascular Health: Beyond the direct influence on blood pressure, sleep apnea can negatively affect the health of blood vessels. Fluctuating oxygen levels and heightened cardiovascular stress are contributing factors to endothelial dysfunction, a state characterized by suboptimal functioning of the inner lining of blood vessels. Endothelial dysfunction is the narrowing, and hardening of arteries, further amplifying the risk of cardiovascular events.

Cognitive Impairment:

  • Sleep Architecture Disruption: Quality sleep is the cornerstone of cognitive function and memory consolidation. Sleep apnea disturbs the typical pattern of sleep, hindering individuals from transitioning through the different sleep phases, especially the deep, rejuvenating stages crucial for cognitive well-being. The repeated interruptions to the sleep cycle impede the brain's ability to undergo crucial processes necessary for memory formation and overall cognitive well-being.

  • Challenges in Concentration and Memory: The cognitive consequences of untreated sleep apnea manifest in daily life through difficulties in concentration and memory lapses, leading to diminished work performance and overall productivity. Memory lapses may be particularly noticeable, impacting short-term and long-term memory recall. Persistent cognitive impairment can have far-reaching consequences, affecting daily functioning and diminishing overall quality of life.

  • Long-term Cognitive Decline: The prolonged impact of sleep apnea on cognitive function raises concerns about the potential for long-term cognitive decline. Chronic sleep deprivation and the associated cognitive impairment may contribute to a heightened risk of neurodegenerative conditions, including Alzheimer's disease. Recognizing and addressing sleep apnea in its early stages becomes crucial to mitigating the risk of enduring cognitive decline and preserving cognitive health.

Metabolic Disturbances: The intricate relationship between sleep apnea and metabolic health unveils a complex interplay beyond nightly disruptions.

  • Disrupted Glucose: Sleep deprivation, often associated with sleep apnea, disturbs the intricate equilibrium of hormones responsible for controlling hunger and feelings of fullness. One significant metabolic repercussion of sleep apnea involves its influence on glucose control. The periodic decreases in oxygen levels during apnea episodes initiate a stress reaction that disrupts the management of blood sugar levels. The result is an increased risk of insulin resistance, a condition where the body's cells are unresponsive to insulin, resulting in elevated blood glucose levels. Left unaddressed, insulin resistance can progress to type 2 diabetes, posing significant long-term health risks.

  • Heightened Cravings and Weight Gain: Ghrelin, the hormone responsible for stimulating appetite, tends to increase, while leptin, which signals fullness, decreases. This hormonal imbalance often translates into heightened cravings for sugary and high-calorie foods. The quest for quick energy fixes becomes a vicious cycle as poor dietary choices contribute to weight gain, further exacerbating metabolic imbalances.

  • Obesity as a Consequence and Contributor: The link between sleep apnea and obesity is bidirectional. On one hand, excess weight, particularly around the neck, can contribute to airway obstruction, exacerbating the severity of obstructive sleep apnea. On the other hand, the chronic sleep deprivation and metabolic disturbances caused by sleep apnea contribute to weight gain. Sleep apnea and obesity amplify each other, creating a challenging scenario for individuals striving to achieve and maintain a healthy weight.

Emotional and Mental Health:

  • Impact on Emotional Regulation: Sleep is intricately connected to emotional regulation, and sleep pattern disruptions can profoundly affect mood. Individuals with untreated sleep apnea may experience heightened irritability, mood swings, and emotional instability. The chronic stress response triggered by apnea episodes can contribute to a state of emotional dysregulation, impacting an individual's ability to cope with daily stressors.

  • Susceptibility to Mood Disorders: The relationship between sleep apnea and mood disorders, such as depression and anxiety, is well-documented. The persistent sleep deprivation and oxygen desaturation associated with untreated sleep apnea create a physiological environment conducive to the development or exacerbation of mood disorders. Addressing sleep apnea becomes a crucial component in managing and preventing the onset of these mental health challenges.

  • Fatigue, Daytime Sleepiness, and Quality of Life: The hallmark symptoms of sleep apnea—fatigue and daytime sleepiness—extend beyond the physical realm and infiltrate emotional well-being. The constant struggle to attain restful sleep leads to a pervasive sense of fatigue, diminishing one's capacity to engage in daily activities enthusiastically. Relationships may suffer as a consequence, as the emotional toll of sleep apnea permeates various facets of life, compromising the overall quality of life.

Conclusion

Sleep apnea is a serious health concern beyond nightly disturbances and disrupted sleep. Its repercussions can permeate various physical and mental health aspects, significantly impacting an individual's overall well-being. Detecting the symptoms and promptly seeking intervention is vital for reducing the potential long-term health hazards associated with sleep apnea.

Dr. Prakashkumar P Bhatt
Dr. Prakashkumar P Bhatt

Neurology

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