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Palindromic Rheumatism - Symptoms, Causes, and Treatment

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Palindromic rheumatism is inflammatory arthritis characterized by episodic joint pain and inflammation. Read this article to know more about the disease.

Medically reviewed by

Dr. Anshul Varshney

Published At March 31, 2023
Reviewed AtMarch 31, 2023

Introduction

Palindromic rheumatism is a type of inflammatory arthritis that is characterized by episodic joint pain and inflammation. It usually causes attacks of pain and inflammation in the joints that wax and wane on their own. In between the attacks, the joints appear normal and the inflammatory attacks do not lead to severe damage to the joints. It is also known as palindromic arthritis.

What Are the Symptoms of Palindromic Rheumatism?

No symptoms usually occur in between the attacks in patients suffering from palindromic rheumatism. The clinical manifestation is entirely different from rheumatoid arthritis which is a type of inflammatory arthritis where the patients complain about joint pain most of the time.

  • The joint, the tendons, and the area surrounding them appear painful, swollen, and stiff during the time of an episodic attack of palindromic rheumatism.

  • The joints may also become warm and tender, and the overlying skin on the joints may appear reddish.

  • These episodic attacks are initiated in one or two hand joints. These joints quickly become stiff, edematous (swollen), and tender.

  • Painful and swollen tendons may also appear along with the swollen joints.

  • These attacks are also known as flares or flare-ups. Attacks can affect one joint to another joint. This flare usually lasts for three to five days. Eventually, this ongoing flare subsides, and the joints and tendons return to normal state.

  • However, frequent these attacks are, they do not cause damage to the joints. In between the palindromic rheumatism attacks, the patients usually feel normal.

  • Fatigue is another common symptom of palindromic rheumatism. The affected individual feels exhausted for a few days to a few weeks. It might affect the individual physically as well as emotionally.

  • It also affects the concentration of the affected person.

The pattern of attack varies for each individual. Attacks in some individuals occur once or twice a year and in some individuals, the attacks might occur every week. In some people, attacks last for a few hours while in some people, they may take several days to subside. Some people might develop nodules beneath the skin of the affected joints.

What Are the Causes of Palindromic Rheumatism?

It is an autoimmune-mediated mechanism in palindromic rheumatism where the joints are mistakenly attacked by the immune system. The inflammation caused due to autoimmune reactions leads to pain, redness, swelling, and extra fluid accumulation in and around the joint spaces of the affected patients. The exact etiology for causing such inflammation is unknown but certain predisposing factors have been found to trigger the response. Genetic factors have also been attributed to its pathogenesis but other triggers such as trauma, injury, certain infections, or hormonal imbalance have also been found to play a role in the pathogenesis of the disease.

Both men and women are affected equally by the condition. Children are rarely affected and there is no age predilection.

How to Diagnose Palindromic Rheumatism?

The diagnosis is usually based on the symptoms of the disease along with hematological tests and imaging scans. The doctor will do a full check-up and examine the joints to exclude other types of inflammatory arthritis. Make sure to visit the doctor during the period of flare.

  • Hematological Tests- Tests forerythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) should be conducted to check the levels of inflammation in the body. Other blood tests such as rheumatoid factor, anti-CCP, and anti-nuclear antibodies can be performed to detect antibodies in a palindromic rheumatism patient.

  • X-Rays- The scans can be done to rule out the disease as well along with other similar conditions.

What Is the Treatment of Palindromic Rheumatism?

The rheumatologist or general physician will suggest certain medications and physiotherapy to treat the condition.

Pharmacological Drugs- Drugs are the mainstay of treatment to treat pain and reduce inflammation, and treat the disease.

  • Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)- These drugs are used to minimize pain, inflammation, and tenderness at the time of attacks. They have certain side effects so it is important to take them at the lowest dose.

  • Corticosteroid Injections- Steroid injection might be suggested by the doctor to reduce the pain in the joints or to reduce inflammation in the tendons. They are directly injected into a muscle or a joint. They quickly show results within two to three days.

  • Disease-Modifying Anti-Rheumatic Drugs- Their mechanism of action is to reduce the symptoms and intensity of the attacks. They have the potential to treat the condition rather than minimize the pain. They are used to prevent the occurrence, frequency, and severity of these attacks.

Exercises- Exercise is very essential to keep the joints healthy but during the attacks, the patient might get fatigued. Therefore, it is very important to set the correct balance between physical exercise and rest. Exercises such as stretching and hydrotherapy exercises (water aerobics or water walking) can be performed to keep the joints working properly.

Balanced Diet and Nutrition- There is no specific diet to treat the condition but being obese will unnecessarily strain the joints more. Therefore, it is important to maintain weight. A balanced diet should be consumed with loads of fresh fruits and vegetables to improve overall health. Fish oils have also been found to reduce inflammation of the joints in some people. Pure fish body oil is considered more beneficial than fish liver oil.

How to Manage the Attack Symptoms?

Certain things can be done to ease the symptoms. If the severity of the pain is too much during an attack, immediately rest the joints. Insoles for the shoes and wrist splints might be helpful to alleviate the pain. Gentle physical exercises should be started once the inflammation has subsided. Consult the doctor regularly.

Cold or heat therapy, such as an ice pack or a hot water bottle, can help to relieve pain and swelling. However, one should never apply them directly on the skin. Certain relaxation exercises and meditation might also help the affected individual. The patient can even consult a physiotherapist for his well-being.

Conclusion

Palindromic rheumatism is a disease that requires immediate attention. More research is required in the field of diagnostics that will help to identify the affected ligaments and joints quickly. A quick diagnosis of the condition will help to better understand the condition and improve ways of controlling it and discovering new treatment modalities.

Frequently Asked Questions

1.

How Dangerous Is Palindromic Rheumatism?

Palindromic rheumatism patients eventually develop Rheumatoid arthritis (RA), which results in irreversible joint damage in half of cases. Men and women are equally affected by palindromic rheumatism, which usually affects individuals in their 20s to 50s.

2.

What Distinguishes Rheumatoid Arthritis From Palindromic Rheumatism?

Palindromic rheumatism patients typically don't experience any symptoms in between flare-ups. Those who have rheumatoid arthritis or other inflammatory arthritis kinds are typically affected by joint difficulties, which sets them apart from this type of arthritis.

3.

Is There a Cure for Palindromic Rheumatism?

Palindromic rheumatism currently has no known cure. However, some lifestyle modifications and medications can help patients feel better overall, manage their symptoms better, and have fewer severe attacks.

4.

How Does One Treat Palindromic Arthritis?

Medications for pain management, anti-inflammatory drugs, and medications for the ailment itself are the main treatments for palindromic rheumatism. To identify the best course of action for the patient, it is critical to collaborate with the doctors as individual responses to therapies vary.

5.

Activities That Are Beneficial for Palindromic Rheumatism?

Exercise is essential for increasing joint flexibility and muscular strength, but weariness can make it difficult for certain people to exercise. Some individuals with palindromic rheumatism find that stretching, yoga, and water treatment are helpful in low-impact workouts.

6.

What Is a Palindromic Arthritis Diet?

Palindromic rheumatism is not impacted by any particular diet; however, it is crucial to control the patient's weight to prevent joint strain. Because potato skin contains mineral salts, eating raw potatoes can help some people with PR feel less pain and discomfort.

7.

Which Kind of Arthritis Hurts the Most?

One of the most excruciating forms of arthritis is rheumatoid arthritis, which affects not just the joints but also the surrounding tissues, including the organs.

8.

Does Exercise Make Arthritis Go Away?

Arthritis symptoms can be lessened by physical activity. For those who have arthritis, gentle movements like tai chi and mild water exercise might be especially beneficial. Together with the physician, physiotherapist, exercise physiologist, or fitness specialist, plan the workout regimen.

9.

Is It Possible to Have Both Rheumatoid Arthritis and Palindromic Rheumatism?

Each person has palindromic rheumatism differently. Some experience sporadic bouts, while others discover that their symptoms go away in between. On the other hand, some people gradually become more problematic and may even get rheumatoid arthritis.

10.

What Is the Duration of Rheumatism?

Unless there is a change in treatment, they may continue for several weeks or months. It is critical to monitor both arthritis treatment and the symptoms, as they are typically trustworthy markers of an impending flare-up.

11.

Which Four Stages of Rheumatoid Arthritis Exist?

Synovitis, pannus, fibrous ankylosis, and bony ankylosis are the four stages of rheumatoid arthritis.


- Phase One: It includes Synovitis. Patients can begin to experience modest symptoms during stage I, such as stiffness and soreness in their joints.


- Phase Two: Pannus.


- Phase Three: Fibrous Ankylosis.


- Phase Four: Bony ankylosis.

12.

Is Rheumatism a Chronic Condition?

The autoimmune illness Rheumatoid arthritis (RA) primarily affects the joints and is chronic (long-lasting). When the immune system, which often aids in defending the body against illness and infection, targets its tissues, RA results.

13.

Does Someone Develop Rheumatoid Arthritis Suddenly?

About 5 to 10 % of RA patients experience a sudden onset of the disease, followed by years or even decades without any symptoms, symptoms that change with time. 15 % or so of individuals with rheumatoid arthritis experience this. Months may pass between flare-ups, during which the patient experiences few or no issues.

14.

Can Rheumatoid Arthritis Be Healed by the Body?

Curing rheumatoid arthritis is not possible. However, clinical research suggests that early therapy with pharmaceuticals known as Disease-modifying antirheumatic drugs (DMARDs) increases the likelihood of symptom remission.

15.

Can a Remission Occur in Palindromic Rheumatism?

Not every patient with PR will progress to RA; only 15 % of individuals experience clinical remission, and 40–50 % of patients experience recurring bouts without chronic joint involvement.

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Dr. Anshul Varshney
Dr. Anshul Varshney

Internal Medicine

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