Introduction
Marijuana is also known as cannabis. Cannabis dependence is also called cannabis use disorder (CUD). Cannabis use disorder is an economic and functional burden to society and the individual. Cannabis dependence is defined as a well-characterized phenomenon that occurs in half of the users of cannabis after stopping or significantly reducing the amount of cannabis product. Cannabis contains tetrahydrocannabinol (THC). The most frequently used illegal psychoactive substance in the world is cannabis. In the past few years, there has been too much rush in hospitals for the treatment of cannabis use disorder. There is an increased need for medication for the treatment of CUD. There is no effective medication for CUD. The medicine that is discovered now may alleviate the symptoms of cannabis withdrawal. The symptom of cannabis withdrawal includes mood disorders, irritability, and depression. The United States Diagnostic and Statistical Manual of Mental Disorders and International Classification of Diseases diagnosed cannabis abuse and cannabis dependence. Approximately four million adults are diagnosed with Cannabis dependence in the United States. The clinical importance of cannabis withdrawal is the possibility that the recurrence of cannabis usage may be preceded by its symptoms. People who simultaneously take multiple drugs and have mental health issues may experience difficult withdrawal.
What Is Marijuana?
Cannabis sativa, a variety of hemp plant that has active cannabinoids that can be classified as psychoactive (like cannabinol), non-psychoactive (like cannabidiol), or inert, is the source of marijuana and the extracts used to make it. The most widely used illegal substance in Canada is marijuana, which is also used to treat various medical diseases' symptoms. However, persistent marijuana usage can lead to dependence, just like with many other substances. CB1 receptors (located mainly in the central nervous system but also found in the lungs, liver, and kidneys) and CB2 receptors (located in the immune system and hematopoietic cells) are two receptors where cannabinoids affect its actions. The psychoactive substance in cannabis is tetrahydrocannabinol (THC). The dried plant material is smoked. The other substances of marijuana, such as natural extract and hash oil, are also smoked or inhaled. The most common method of marijuana intake is through inhalation, as the active chemicals travel quickly from the lungs to the brain. The cannabis effect lasts less than two hours when smoked.
What Is Cannabis Dependence?
Cannabis dependence is the cannabis addiction. The reduction or cessation in the cannabis amount causes cannabis withdrawal in the users. Cannabis withdrawal symptoms are typically more severe and last longer in people with cannabis use disorder (CUD) than those without CUD. This is most likely due to their increased frequency and volume of cannabis use as well as their increased THC exposure. CUD is defined as continued cannabis use despite detrimental impacts on the user or other's physical or mental health and social functioning. The Diagnostic and Statistical Manual of Mental Disorders and the International Classification of Diseases are two diagnostic systems that categorize and specify the severity of the disorder. According to the studies, more than 20,000 regular cannabis-dependent users are estimated. The prevalence of cannabis withdrawal symptoms is higher in users who take cannabis daily. The number of patients with cannabis withdrawal is increasing from 54 % to 87 %.
What Are the Symptoms Of Cannabis Withdrawal?
The abrupt cessation or reduction in the use of Cannabis products causes Cannabis withdrawal symptoms. The symptoms are seen in heavy cannabis users.
The following are the symptoms of cannabis withdrawal:
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Mood changes.
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Suicidal thoughts.
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Breathing problems.
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Increased heart rate.
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Nausea and vomiting.
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Anxiety.
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Sleeping problems such as insomnia, sleeping disturbances, and strange dreams.
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Anger and irritability.
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Restlessness.
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Headache.
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Abdominal pain.
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Tremors.
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Sweating.
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Decreased appetite.
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Decreased weight.
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Craving for weed.
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Fever.
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Shakiness.
What Is Marijuana Detox?
Marijuana detox is the complete cessation of marijuana. The marijuana detox is difficult because of marijuana withdrawal symptoms. No medication can be specifically successful in marijuana detox. The support of pharmacological treatment helps in reducing cannabis dependence and relapse. It might reduce dependence.
The following are some medicines used to control withdrawal symptoms and reduce marijuana dependence:
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Cannabis Agonists - CB agonists work directly on the brain to suppress withdrawal symptoms. It is used as a substitute for weed. Cannabis Agonists are oral THC and Dronabinol.
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Anti-depressants - Bupropion, Nefadazone, and Fluoxetine are some anti-depressants.
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Cannabis Antagonist - Rimonabant is a cannabis antagonist.
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Opiate Antagonist - Naltrexone are opiate antagonist.
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Anxiolytic - Busprione are anxiolytic used to depress withdrawal symptoms.
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Mood Stabilizers - Lithium and Divalproex are mood stabilizers used for treating depression or mood swings.
How Long Does Marijuana Detox takes To Work?
During a detox, the body eliminates THC and its metabolites, which are the byproducts produced when THC is broken down in the body. THC is mainly stored in fat cells and is gradually released over time. As a result, the elimination of THC from the body can take days to weeks, depending on several factors. There is no guaranteed method to speed up the detox process, as it is primarily dependent on the body's natural metabolism. However, some strategies may help support the detoxification process, such as:
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Staying Hydrated: Drinking plenty of water can aid in flushing out toxins through urine.
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Exercising: Engaging in physical activity can boost metabolism and promote the breakdown of fat cells where THC is stored.
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Eating a Healthy Diet: Consuming nutritious foods and avoiding high-fat, processed foods may support overall detoxification.
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Allowing Time: Ultimately, the body needs time to naturally eliminate THC and its metabolites. Abstaining from marijuana use and adopting a healthy lifestyle can help facilitate the detox process.
Conclusion:
In conclusion, marijuana detox is a crucial step for individuals seeking to overcome cannabis dependence and reclaim control over their lives. As discussed in this article, marijuana withdrawal symptoms can vary from mild to severe and may include irritability, anxiety, insomnia, and loss of appetite. While the process of detoxification can be challenging, it is important to remember that professional support and guidance are available to assist individuals throughout this journey. By acknowledging the symptoms, developing a support network, and adopting healthy coping mechanisms, individuals can successfully navigate the withdrawal period and move towards a healthier, balanced life free from cannabis dependence.