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I have dermatitis herpetiformis for six years. Will long term Dapsone intake cause resistance?

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Patient's Query

Hello doctor,

I have dermatitis herpetiformis symptoms for six years. Currently, my age is 27. And I am taking Dapsone tablets. My doctor recommended me to eliminate wheat food and a gluten-containing diet as DH causes gluten sensitivity. I want to know, can I continue taking Dapsone for life-long instead of not eliminate any food. I searched on the internet that I can take Dapsone for life long. But the doctor says if you take Dapsone always then, it can be ineffective after some time. So what to do? Should I meet an allergist or nutritionist? Can this disease be cured fully? Or can I take Dapsone regularly and eat all kinds of foods?
Answered by Dr. Dhepe Snehal Madhav

Education:

MBBS

Professional Bio:

Dr. Dhepe Snehal Madhav is a Dermatologist and Venereologist specializing in the diagnosis and treatment of various skin conditions. She is experienced in evaluating patients, conducting thorough screenings, and formulating personalized treatment plans to ensure optimal skin health. She delivers compassionate and comprehensive dermatological care.

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Hello,

Welcome to icliniq.com.

Dermatitis herpetiformis is associated with gluten-sensitive enteropathy. Immunological response to chronic stimulation of gut mucosa by dietary gluten plays a significant role in the induction and persistence of disease. The major auto-antigen associated is epidermal transglutaminase. Autoimmune factors, genetics, and environmental factors play a role. Other environmental factors that trigger DH are the ingestion of gluten (cereals such as wheat, rice, and barley). Also, iodine-containing diets such as shellfish, exposure to iodine during surgical procedures can induce flare-ups. Do you have a pruritic rash or intense itching? What is the extent of involvement? Do you have erythematous papules, hives, or vesicles? Are your iron and folate levels equals? Do you have B12 or zinc deficiencies, abdominal discomfort, or any autoimmune disorder? A gluten-free diet is the treatment of choice for DH. After 1 or 2 years, it may reduce or eliminate the need for medication. It is wise to start the dose at 25 to 50 mg in adults and slowly increase the dose that keeps patients comfortable and without significant side effects. Regular follow-up is required with the blood report in the first three months of Dapsone therapy. Topical steroids can be used in reducing the symptoms. Do you have any lesions?

Medically reviewed by Dr. Vinodhini J.
Published At December 17, 2020
Reviewed At August 28, 2023

Education:

MBBS

Professional Bio:

Dr. Dhepe Snehal Madhav is a Dermatologist and Venereologist specializing in the diagnosis and treatment of various skin conditions. She is experienced in evaluating patients, conducting thorough screenings, and formulating personalized treatment plans to ensure optimal skin health. She delivers compassionate and comprehensive dermatological care.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality

Education:

BDS

Professional Bio:

Dr. Vinodhini J. is a Dental Surgeon with extensive years of clinical experience. She specializes in the diagnosis, prevention, and treatment of dental and oral health issues, including restorative, surgical, and cosmetic procedures. With a patient-centered approach, she focuses on maintaining oral health, alleviating discomfort, and enhancing smiles. Her expertise ensures comprehensive care tailored to each patient’s dental needs and overall wellbeing.

This doctor is not available for online consultations on the platform anymore.

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Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Dhepe Snehal Madhav
Dr. Dhepe Snehal Madhav

Venereology

Education:

MBBS

Professional Bio:

Dr. Dhepe Snehal Madhav is a Dermatologist and Venereologist specializing in the diagnosis and treatment of various skin conditions. She is experienced in evaluating patients, conducting thorough screenings, and formulating personalized treatment plans to ensure optimal skin health. She delivers compassionate and comprehensive dermatological care.

This doctor is not available for online consultations on the platform anymore.

Consult other doctors in the same speciality
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