What treatment would you recommend for endometrial hyperplasia?

Question

Hi doctor,

Would you be kind to give us a second opinion based on attached files? Please find the attached pathology report of my wife where basically she was given two options. I have uploaded the findings of endometrial hyperplasia. The options given are hormones for life, Progesterone with three to four months checkup and follow ups and hysterectomy.

Answer 1

Hi,

Welcome to icliniq.com.

I have gone through the reports and the history of illness provided (attachment removed to protect patient identity).

Considering the fact that the submucosal fibroid is quiet small in size and the histopathology is suggestive of proliferative endometrium, it is advisable that the patient goes for hormones.

On the other hand, considering the age, having crossed the fertile age and hormones having its inherent issues hysterectomy is advised.

Now coming to my impression, given a choice to decide as a medical practitioner, I would opt for hysterectomy.

For further information consult a medical oncologist online.

Answer 2

Hi,

Welcome back to icliniq.com.

Progesterone is available in oral, injectable and intrauterine device forms.

Yes, it all depends on the presence of atypia or in simple words deformed abnormal cells and 10 means complex with atypia.

In simple hyperplasia without atypical cells, it is unlikely that it will go for acute transformation into malignancy.

We prefer repeat examination every three months. If there is no response for six months, hysterectomy should be opted and if there is a response, then the medicine should be continued for 12 months.

These are the two time tested modalities of treatment. We prefer not to comment on alternative forms of medicine.

As mentioned, if no response after six months, then go ahead with hysterectomy.

For further information consult a medical oncologist online.