Q. Following delivery and blood transfusion, developed blisters on face. Why?

Answered by
Dr. Gaurang Gupta
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Aug 10, 2016 and last reviewed on: Aug 19, 2022

Hi doctor,

I delivered a baby through normal delivery 15 days before, and I got one unit of blood transfused. Yesterday, I got rashes and blisters only on my face, which keeps increasing. What to do? Please help. I am taking antibiotics, multivitamins, calcium, and iron supplements. Kindly help.



Welcome to

Blood transfusion and antibiotics are the two reasons, which can cause rashes in your situation. You have to wait and watch. If the problem increases, you need to take steps like changing the antibiotics and evaluating blood transfusion. But, if the problem resolves itself in four to five days, then no need to worry and continue your medicines.

If you can send me photos of your problem, I can assess the condition and give you better advice.

Hi doctor,

Thanks for your reply. I am sending my current photos. I am given Ceftum 500, Aciloc, multivitamins, Calcium, and Iron tablets. I have five post-delivery stitches. The blisters have not expanded since yesterday.



Welcome back to

As I said, it could be a drug reaction. But, by seeing your photos (attachment removed to protect patient identity), herpes is another disease, which can be suspected.

Herpes is very common after pregnancy, and physical stress is a triggering factor for that. I would suggest you consult a local dermatologist and rule out herpes. If it is not herpes, then it is a drug reaction. But, as you said, it is not increasing even after you have not stopped.

The second thing that gives me doubt is that if you see your face, are the lesions present only on one side of the face? So, I would suggest that you visit the local dermatologist because it is complicated to say 100% that it is herpes or a drug reaction in your photos. It is unlikely that it could be something else. So, there are only two diseases, which we have to rule out either herpes or drug reaction. I rule out blood transfusion-associated reaction because it would be widespread and severe if blood-related. Also, tell me, is there any pain? Have you got a mouth ulcer and any other body part involved? Is this a sudden reaction? Did it come after two to three days of medicine?

Revert with the answer to the above questions to help you.

Hi doctor,

Thanks for your reply. I am a little relieved as I was worried about a possible reaction due to a blood transfusion. My answers to the queries are as follows. I do not have any pain. Yes, one tiny mouth ulcer is present, and no other body part is involved. It came two to three days after starting the medicine. It began in a small area below the right eye and on the upper lip with a little inside nose and then expanded yesterday morning. After that, I stopped applying the Soframycin gel suggested by the doctor at the hospital. Now, I feel that the color has become dark in some areas. Would you please guide me?



Welcome back to

You have to see a dermatologist in person to confirm whether it is herpes or not. Because in drug reaction only face involvement will not be present. Drug reactions will affect other parts of the body too. It is very difficult to say with photos because you do not have a typical herpes lesion but a high possibility of herpes. At present, my diagnosis is more in favor of herpes than drug reaction.

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