High Serum Iron

High serum iron occurs when the body's regulatory system fails to keep iron within the normal limits. If left untreated, it might cause abdominal pain, bronze-colored skin, tiredness, weakness, weight loss, cirrhosis of the liver, and pancreatitis.

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Please suggest ways to reduce high iron levels.

Query: Hi doctor,My mother has been transfused with at least 11 to 12 units of blood during a period of two months. This was done on a false diagnosis of iron deficiency anemia. It was a false diagnosis because the transferrin receptor was never used to come to this diagnosis. She has had elevated CRP for ...  Read Full »

Dr. Prakash H. M

Answer: Hi,Welcome to icliniq.com.Based on your query, my opinion is as follows,Normally in hemochromatosis (iron deposition disease), serum transferrin, iron, and ferritin levels will be usually high. All the symptoms and signs point towards hemochromatosis, possibly due to iron overloading secondary to mu...  Read Full »

I am feeling a bit of weakness and would like to know what is the maximum dose of iron supplements a man can take?

Query: Hello doctor, I am a 31 year old male, who is 1.8 m tall, and I weigh 106 kg. I have a problem recently. I went to a dentist for an abscess, and I had blood a bit removed, so I felt a bit weak. And finally some days after, I felt I needed iron supplements. I took one 100 mg and then took another 100...  Read Full »

Dr. Shobhit Shah

Answer: Hello, Welcome to icliniq.com. To know about iron overload, get serum ferritin and iron levels checked. In iron-deficiency, an elementary iron of 100 to 200 mg per day is advised.In a normal person, daily allowance is hardly 25 mg per day. You just stop your iron supplements and have these tests.For...  Read Full »

How to reduce the levels of iron and ferritin?

Query: Hello doctor, I am a 61 year old male. For many years, I was treated for hemochromatosis. Then, about 12 years ago, I had a genetic test. The results prompted the hematologist to abruptly stop the recurring phlebotomies. I do not recall the test result and apparently, it cannot be located. But, I r...  Read Full »

Dr. Desai Santosh Badaku

Answer: Hi, Welcome to icliniq.com. I understand your concern. Your iron saturation and serum ferritin is high and these are suggestive of iron overload or hereditary hemochromatosis (HH). You talked about a test that was done and then the hematologist stopped the phlebotomy. I think, probably he mus...  Read Full »

How to reduce my serum ferritin level?

Query: Hi doctor, My ferritin level is 1500, and I want to bring it down to 150. How much will one DFO IV session or each Exjade pill reduce the ferritin level on an average? I am a healthy individual, and I do not have HIV, HCC, or any other disease.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Your serum ferritin is high, so the cause should be found out first. It can be hemochromatosis, in which excess iron is stored in the bone marrow. Deferoxamine is used for increased iron storage in thalassemia patient. For high ferritin, phlebotomy is also another mo...  Read Full »

I am a 50-year-old woman with migraine-like headaches, nausea, and digestion issues on a daily basis. Please help.

Query: Hello doctor, I am a 50-year-old women and I am not well for a couple of weeks. I am experiencing migraine like headaches, nausea and digestion issues on a daily basis. My doctor thinks it may be due to stress and put me on a two week heart monitor. However during routine tests, my serum iron and ...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello, Welcome to icliniq.com. I read your query and can understand your concern. Vitamin B12 deficiency should be ruled out by serum B12 estimation. However, a psychiatrist needs to be consulted if you have an anxiety issue. Your liver, kidney profile, and electrolytes are within normal range. S...  Read Full »

I have a swollen lymph node in the armpit. Does it indicate any health issue?

Query: Hello doctor, I have swollen lymph node in the armpit with very little pain. I have been experiencing fatigue and weight loss for the last few weeks. I have gone through some routine laboratory tests and found that some test results are out of the normal range. Iron profile: iron 153 mcg/dL, UIBC 96...  Read Full »

Dr. Sagar Ramesh Makode

Answer: Hello, Welcome to icliniq.com. Serum iron is a bit on the high normal side and TIBC (total iron-binding capacity) and UIBC (unsaturated iron-binding capacity) is on the lower side. The rest of the reports are fine. ESR (erythrocyte sedimentation rate) is normal, so it makes the possibility of chro...  Read Full »

My iron saturation percentage is higher than normal. Does it mean I have hemochromatosis?

Query: Hi doctor, I am a 52-year-old male (5 foot 7 inches, 157 pounds) with no symptoms. I had some routine annual lab tests performed three months back, I had an elevated Ferritin level of 325.9 (normal is 40 to 250 ng/mL). So I had more comprehensive lab tests done last week. Please see attached lab re...  Read Full »

Dr. Mian Shah Yousaf

Answer: Hello, Welcome to icliniq.com. I reviewed all your tests (attachments removed to protect the patient's identity). Your serum transferrin saturation suggests hemochromatosis, but it is an initial screening test, and your ferritin is not that high. Your liver enzymes are also normal, so there is nothi...  Read Full »

Can serum iron levels increase from taking iron supplements?

Query: Hi doctor, I am 44-years-old female. I am a vegetarian. My current medications are fish oil, multivitamin, vitamin C supplements, and a high dose of vitamin B for my neuropathy. I drink beer or wine two servings three times a week. I have an increased iron value with no other symptoms. I consulte...  Read Full »

Dr. Abdul Aziz Khan

Answer: Hi,Welcome to icliniq.com.I agree with your doctor that iron supplementation may cause high serum iron since you have normal ferritin and hemoglobin. So, I suggest stopping iron and repeat CBC (complete blood count), iron, and ferritin after three months. And kindly upload your reports for review.Th...  Read Full »

Why does the sclera of my eyes have a blue hue to them?

Query: Hi doctor, I am consistently doing tests to know my iron levels every month and the results are confusing. I have low ferritin. I am exhibiting classic signs of iron deficiency and even my sclera of eyes have a blue hue on them. But my serum iron levels are consistently high which causes my saturat...  Read Full »

Dr. Alexander Davis

Answer: Hi, Welcome to icliniq.com. You need to consult an endocrinologist for having a high transferrin saturation greater than 50 percent. It creates non-transferrin-bound iron (NTBI) which is toxic and creates damage to certain cells in the body through an oxidation process. When your transferrin s...  Read Full »

Will increased iron saturation cause damage of internal organs?

Query: Hello doctor, I am 20 years old. Today I got lab results that show my iron saturation is 73% and my iron serum is 278 ug/dl. I am 6 feet tall and have lost weight down to 127 pounds. I have joint pain, headaches, digestive issues, low appetite, and depression. My mom got me an appointment with a h...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Your serum iron level is high. So we have to rule out iron over storage means hemochromatosis like picture. For that, serum ferritin and transferrin saturation have to be done. Your serum ferritin level is normal, So iron storage seems less likely. However, investigate...  Read Full »

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