Recently Answered Questions
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I have grayish skin on my face and an increased ferritin level. Why?
Query: Hi doctor,I have grayish skin on the face, but my hemoglobin is normal. I have leucocytes at 11.1, ferritin 402, and C-reactive protein 13. I am on Zoloft Risperdal and Remeron. Kindly give your opinion. Read Full »
Answer: Hi, Welcome to icliniq.com. I can understand your concern. According to your statement, you have been suffering from grayish discoloration of the skin in the face. Again, according to your investment reports, your leucocytes level and CRP (C-reactive protein) level are above normal, and your fe... Read Full »
I have high ferritin levels at the age of 50. Please advise.
Query: Hello doctor,I am a 50-year-old female who has had an elevated ferritin level for many years now. My last ferritin level was 342, 20 days back. My ferritin level has been as high as 390. My TIBC, UIBC, iron, and iron saturation have always been within normal range. My glucose has always ranged from ... Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hello, Welcome to icliniq.com. Elevated ferritin could be from congenital hemochromatosis but HFE gene mutation is negative, so it is excluded (attachment removed to protect patient identity). Secondly, a hemolytic condition also can be a possibility but serum LDH (lactic acid dehydrogenase), reti... Read Full »
Can I be a carrier or patient of hereditary hemochromatosis?
Query: Hello doctor,I have received a blood test back that I am confused about. I have previously been diagnosed with hereditary hemochromatosis but a new physician recently did the genetic test and indicated that I only had one of the genes present and thus was a carrier and not a patient. The blood test ... Read Full »
Answer: Hello, Welcome to icliniq.com. I have gone through your blood test results (attachment removed to protect patient identity). Your blood picture shows that the iron which is absorbed is not being utilized properly. Your transferrin saturation level of 56 % is high but not more than 62 %, which ... Read Full »
I want to reduce my ferritin levels. Please help.
Query: Hi doctor, My ferritin level is 1500, and I want to bring it down to 150. How much will one DFO IV session or each Exjade pill reduce the ferritin level on an average? I am a healthy individual, and I do not have HIV, HCC, or any other disease. Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hi, Welcome to icliniq.com. Your serum ferritin is high, so the cause should be found out first. It can be hemochromatosis, in which excess iron is stored in the bone marrow. Deferoxamine is used for increased iron storage in thalassemia patient. For high ferritin, phlebotomy is also... Read Full »
What is the cause of persistent increase in liver enzymes?
Query: Hi doctor, I am 23 years old. It has been more than a year my liver function test result remains high. I have been tested for hepatitis A, B, C, E, and autoimmune hepatitis, but the result all came out negative. My doctor told to take blood test regularly. But, it has been almost a year now, the res... Read Full »
Answer: Hello, Welcome to icliniq.com. I can imagine that you must be very concerned about your persistent elevation of the liver enzymes. As you already have viral etiologies excluded this is time to look for other things which could lead to persistent elevation of the liver enzymes. Notably the Wilson, ... Read Full »
How can I get treated for hereditary hemochromatosis?
Query: Hello doctor, I am a 49-year-old woman. I was diagnosed with hereditary hemochromatosis a decade ago. I have had TSAT in the 80 % range since then, and this has been dismissed as irrelevant by my doctor and hospital. Their advice was to wait till I got to Ferritin 400 micrograms per liter and start ... Read Full »
Answer: Hello, Welcome to icliniq.com. I have read your query and understand your concern. Yes, hemochromatosis may cause conductive cardiac problems. But as such present heart rate and blood pressure in the report (attachment removed to protect the patient's identity) you provided are normal. Yes, sinus ... Read Full »
Do I have ferroportin disease if my ferritin level and transferrin saturation are high?
Query: Hello doctor, I am a 29-year-old male, and I fear that I might have ferroportin disease. I persistently have high ferritin levels, and my transferrin saturation is also mildly above the normal range. I have also looked at my genotyping on chromosome 2 and noticed a single nucleotide mutation for m... Read Full »
Answer: Hello, Welcome to icliniq.com. Having H63D (histidine at amino acid position 63) carrier does not indicate a diagnosis of hemochromatosis. Similarly, you have one of the gene alleles for ferroportin disease. However, the transferrin saturation should be low in ferroportin disease. On the... Read Full »
How is polycythemia different from hemochromatosis?
Query: Hello doctor, Is there an association between polycythemia and hemochromatosis? I have a high Hb of 18 and hematocrit of 51 %. I am a student and found to have incidental polycythemia. I tested for all myeloproliferative neoplasm and the bone marrow biopsy is negative for MPN. However, I was tested ... Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hello, Welcome to icliniq.com. Usually, in hemochromatosis, storage iron is increased, that is serum ferritin. So you can investigate with serum ferritin as well. If you have myeloproliferative neoplasm-like polycythemia, then usually it can be clear from bone marrow study and JAK2 mutation. It ... Read Full »
How to reduce the levels of iron and ferritin?
Query: Hello doctor, I am a 61 year old male. For many years, I was treated for hemochromatosis. Then, about 12 years ago, I had a genetic test. The results prompted the hematologist to abruptly stop the recurring phlebotomies. I do not recall the test result and apparently, it cannot be located. But, I re... Read Full »
Answer: Hi, Welcome to icliniq.com. I understand your concern. Your elevated iron saturation and serum ferritin levels suggest the possibility of iron overload or hereditary hemochromatosis (HH). The test you mentioned, followed by the hematologist's decision to halt phlebotomy, could imply the detection o... Read Full »
Will increased iron saturation cause damage of internal organs?
Query: Hello doctor, I am 20 years old. Today I got laboratory results that show my iron saturation is 73% and my iron serum is 278 ug/dl. I am 6 feet tall and have lost weight down to 127 pounds. I have joint pain, headaches, digestive issues, low appetite, and depression. My mom got me an appointment wi... Read Full »
Dr. Goswami Parth Rajendragiri
Answer: Hi, Welcome to icliniq.com. Your serum iron level is high. So we have to rule out iron over storage means hemochromatosis like picture. For that, serum ferritin and transferrin saturation have to be done. Your serum ferritin level is normal, So iron storage seems less likely. However, investigate... Read Full »