My CBC report shows a sudden increase in WBC with reduced RBC count. Is there any concern?

Hello doctor,

I am concerned about my recent CBC results. My monocytes are high at .79, and also my hematocrit and platelets are gradually decreasing. I saw my primary care physician for my elbow, arm pain, and had my annual CBC. Then a few weeks later, I had blood in my urine. My doctor ordered another CBC and showed increased monocytes and no infection on urinalysis. Urine culture is also negative.

A week later, the third CBC showed an increase in WBC from 4.9 to 6.9, and some encouraging levels were labeled low. Also, immature granulocytes are increased to 0.02. I am just making sure that there is not a process starting. I appreciate any information. Please help.

Thank you doctor,

I will send you all my CBC reports. I think they look normal, and my concern is about the increase in WBC and lower RBC counts. I have not seen blood in my urine and no bacteria present.

I understand that numbers will fluctuate, and my concern is the big jump in WBC in one week (from 4.9 to 6.9). My monocytes decrease within a week from 14% to 12%, but absolute monocyte increased from 0.68 to 0.79 (reference range is 0 to 0.80), and that scares me again with no sickness whatsoever. I am concerned about chronic leukemia or something like that.

I am fairly healthy and never smoked or drank. I had a colon tubular adenoma pre-cancerous polyp of 5 mm at 37 years and had normal colonoscopies. All have been clear for 10 years now. I was young, but my grandmother died of colon cancer, so probably a heredity reason.

Thank you doctor,

I was just worried because the hemoglobin that had gone down from 14.5 to 13.5, and the monocytes increase. And I was not sure if a gradual increase and decrease matters. I appreciate your knowledge and experience and will not worry.