ADVERTISEMENT

Q. HIV RNA was negative on 21st day? Can it be positive later?

Answered by
Dr. Basti Bharatesh Devendra
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Aug 09, 2017 and last reviewed on: Oct 05, 2019

Hi doctor,

I had unprotected sex with a woman for two to three minutes around four weeks ago. I took HIV 1 RNA test on 11th day which was negative. Again I took complete STD panel tests on 21st day with HIV-1 RNA and HIV fourth generation tests, all of the results were negative. But, I can notice small rashes near tip of my penis which are appearing and going away for the past couple of days. Am I HIV positive? I am worried. Can HIV RNA be positive after negative at 21st day?

ADVERTISEMENT
#

Hi,

Welcome to icliniq.com.

  • I have gone through the photo (attachment removed to protect patient identity). Though the photo is not clear, I can make out slight redness on the glans. It may be due to irritation or fungal infection.
  • Do not over clean the area. Clean the area with warm water twice daily. Observe if any rash develops.
  • The chance of transmission of HIV (human immunodeficiency virus) by single unprotected intercourse with a positive person is 1/200 to 1/1000. Here, it is low. She may be negative too. Then the chance is nil.
  • HIV-1 RNA PCR is sensitive after 7 to 10 days. So, the chance of HIV-1 is almost nil.
  • Duo test is considered sensitive after one month. It detects both antigen and HIV 1 and 2 antibodies. Some consider conclusive after one month.
  • You can go for HIV 1 and 2 RNA PCR at this stage. The chance of HIV-2 is very rare.
  • You can get the women's history or get her tested to allay fears totally.

For further information consult a HIV AIDS specialist online --> https://www.icliniq.com/ask-a-doctor-online/HIV-AIDS-specialist

Hi doctor,

The redness has gone away now. I observed it in the morning. It has become normal. Could you please tell can I relax as the RNA test is negative? Is there any case where RNA test has turned positive later after negative at 20 days? I am planning to take Duo test on 30th day. Can I be relaxed if it comes negative?

#

Hi,

Welcome back to icliniq.com.

  • It is good if the rash has subsided. Observe the area. The rash is not related to HIV. You can allay fears about HIV and rash.
  • HIV-1 RNA PCR is very sensitive (more than 99%) after 10 days exposure. The chances of it coming positive later is almost nil.
  • It does not detect HIV 2. So, you can go for HIV 1 and 2 RNA PCR.
  • HIV Duo after one month is considered conclusive by many. With given history and tests it may be considered conclusive after one month.
  • You can go for final antibodies test (HIV 1 and 2) after three months to totally be free from anxiety. The chance of HIV tests becoming positive later is nil.

For further information consult a HIV AIDS specialist online --> https://www.icliniq.com/ask-a-doctor-online/HIV-AIDS-specialist

Hi doctor,

I have attached pictures with red dots. Are these related to HIV?

#

Hi, Welcome back to icliniq.com.

I have gone through the photos (attachment removed to protect patient identity).

  • There is no significant rash now. It may be due to irritation or fungal infection. Just clean the area with warm water twice daily. Wear loose cotton inner wears.
  • These are not related to HIV. You can allay fears of HIV.

For further information consult a HIV AIDS specialist online --> https://www.icliniq.com/ask-a-doctor-online/HIV-AIDS-specialist

Hi doctor,

My HIV 1 RNA and 4th generation tests on 31st day came as negative. Can I relax now?

#

Hi,

Welcome back to icliniq.com.

  • With the given history, details, test reports I would take it as HIV negative.
  • The chances of HIV tests coming positive later is nil. You can allay fears of HIV.

For further information consult a HIV AIDS specialist online --> https://www.icliniq.com/ask-a-doctor-online/HIV-AIDS-specialist

Hi doctor,

I had one more duo test on 52nd day after exposure and it came negative. But, I am having body pains for three days and yesterday a lymph node near my groin got swollen and I got rash on penis again. Is this due to HIV?

#

Hi,

Welcome back to icliniq.com.

  • There is no need for repeating the duo test. There will be no difference. It is better to get the test after three months to have conclusive results. It is negative reiterate that you are free from HIV.
  • The fungal infection or allergic rash is known for recurrence. If the rash is different from earlier rash, you can send clear photos for clarification. Otherwise follow same treatment.
  • Any simple infection in genital area or lower limb can lead to inguinal lymph node swelling. So, do not relate it to HIV. The symptoms are not due to HIV. Allay fears of HIV.

For further information consult a HIV AIDS specialist online --> https://www.icliniq.com/ask-a-doctor-online/HIV-AIDS-specialist

Hi doctor,

I have attached the pictures. Do I need to believe my HIV 1 RNA at 31 days and duo test at 52 days to be conclusive? I have seen many doctors saying six weeks duo is conclusive. Could you please advise me? Is RNA test conclusive and accurate? Have you seen any one turned positive after negative duo at seven weeks?

#

Hi,

Welcome back to icliniq.com.

I have gone through the photos (attachment removed to protect patient identity).

  • It appears to be either due to fungal infection or irritation. Clean the area with warm water twice daily.
  • You can apply Clotrimazole cream like Candid cream after consulting your doctor.
  • HIV RNA PCR after 10 days exposure and duo test after one month is very sensitive test. It is considered conclusive by many.
  • The chances of tests coming positive later is nil. You can allay fears of HIV.
  • To relieve your anxiety and get final conclusive result, it is better to get tested after three months.

For further information consult a HIV AIDS specialist online --> https://www.icliniq.com/ask-a-doctor-online/HIV-AIDS-specialist


Was this answer helpful?

 | 

Same symptoms doesn’t mean you have the same problem. Consult a doctor now!



Related Questions:
Are my symptoms indicative of HIV infection?

.. acidity problems are non-specific symptoms and are not related to HIV (human immunodeficiency virus) infection. The risk factors for HIV infection is having sex with unknown partners, whose HIV status is not known, or through blood transmission. I...   Read full

I have fungal infection on penis with testicular pain. Kindly help with medications.

Hello doctor, I have prescribed Candid B ointment for penis fungal infection ... Switch to plain Candid cream for fungal infection ......   Read full

Are my symptoms due to HIV infection? I had a high-risk exposure 15 months ago.

.. kits used to diagnose HIV are highly sensitive and specific and gives accurate results. The majority of the people who are infected with HIV (human immunodeficiency virus) develop antibodies by three months, and even in the rare instances of late ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read


Monkeypox Virus - Symptoms, Diagnosis, Treatment, Complications, and Prevention
Monkeypox is a zoonotic viral disease. This virus got its name as it was first noticed in laboratory monkeys in the late...  Read more»
Tomato Fever - Causes, Symptoms, Diagnosis, Treatment, and Prevention
Tomato fever is an unidentified and fast-spreading type of viral infection seen in young children. Scroll down to know m...  Read more»
Histrionic Personality Disorder - Causes, Signs, Symptoms, Diagnosis and Treatment
Histrionic personality disorder causes variations in the thinking ability of a person. Read this article to know more.  Read more»

Ask your health query to a doctor online?

Ask a HIV AIDS Specialist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.