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Which test is best for early HIV detection?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I had unprotected sex four weeks ago. Later on, I cross-checked with the girl, and she stated she does not have any disease. But still, I am worried. After three weeks, I have checked with the P24 antigen test, the test value is 0.0, and it is non-reactive. By the fourth week (28th day), I have checked with the HIV 1 and HIV-2 antibody test, and the final results are non-reactive. HIV (Human Immunodeficiency Virus) 1/2 P24 combo test CMIA method - 1.8, which is reactive. The immunochromatography method is non-reactive and flow-through. What could be the reason for the CMIA (Chemiluminescent Microparticle Immuno Assay) test showing as reactive? By considering these tests, what would be the accuracy of HIV status as negative? I have had a throat infection alone for the last two weeks. Is that a symptom of HIV? What is the early conclusive test that I can go with?

Hi,

Welcome to icliniq.com.

It could be a false positive. You have more than 95 percent chances of being negative. A sore throat may or may not be a symptom of HIV (Human Immunodeficiency Virus). Go for a Western blot test and an HIV RT- PCR (reverse transcriptase polymerase chain reaction) test to confirm the status of HIV.

I hope this helps.

Thank you.

Medically reviewed byiCliniq medical review team

Published At April 9, 2017
Reviewed AtDecember 26, 2025

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