Q. I have hypothyroidism and Hashimoto's and feel fatigued after a year of treatment. Why?

Answered by
Dr. Zulfiqar Ahmed
and medically reviewed by Dr. Hemalatha
This is a premium question & answer published on May 03, 2020 and last reviewed on: Mar 30, 2021

Hi doctor,

I have hypothyroidism and Hashimoto's thyroiditis. My doctor tested my TSH levels and treats me with Levothyroxine. I have extreme fatigue after taking this treatment for a year though my TSH is in a normal range. My doctor told me that freeT4 and reverse T3 are not important parameters to test them. I am afraid of whether I need to consult an endocrinologist or continue taking the same treatment. I had a TSH level of 9.8 mIU/L and it got down to 0.08. Now my TSH is in the range of 3.8 mIU/L. I am taking Levothyroxine 112 mcg daily.



Welcome to

Some people taking treatment for hypothyroidism still experience symptoms even if the blood tests show normal thyroid hormone levels. The reason behind this is complex but the bottom line is that a normal TSH (thyroid stimualting hormone) level does not mean that all your symptoms will go away. Evidence suggests that it is not uncommon. Levothyroxine is a gold standard treatment for hypothyroidism but many people fail to understand its physical benefits of this treatment. So try to reduce your TSH levels if you are still having symptoms. For this, you can increase your medication. If you are still symptomatic, then you can change the medicine of Thyroxine. You can try to take T3 supplements instead of T4.

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