Patient's Query
Hi doctor,
I would like someone to review my CBC report. The report shows high immature granulocytes. This was a routine annual draw.
Kindly help.
Hi,
Welcome to icliniq.com.
I understand your concern.
From your CBC (complete blood count) reports (attachments removed to protect the patient's identity), there is a slight increase in immunoglobulin levels, which is insignificant. The rest of your parameters are in range. Go ahead with vaccination.
I hope I have cleared your doubts.
Thank you.
Patient's Query
Hi doctor,
Thank you for the reply.
I am concerned because online information states that a healthy individual should not have these in the blood and can be a sign of a potentially active infection or cancer.
Please guide.
Hi,
Welcome back to icliniq.com.
You can rule out infections by ESR (erythrocyte sedimentation rate) and CRP (C-reactive protein) tests.
The word "leukemia" means white blood cell cancer in the peripheral blood. "Leukemia" is a relatively old term. Nowadays, it is called hematopoietic and lymphoid neoplasm. A good share of circulating white cells comes from lymphoid tissues such as lymph nodes, the spleen, the thymus, etc. And the rest of the cells come from bone marrow. Lymphoid tissue is present all over the body, even in the intestine, lungs, liver, etc.
The neoplasms of lymphocytes, white blood cells, are called lymphomas, which are rarely present in the blood. They are present in lymphoid tissue. However, they do infiltrate blood and bone marrow at some later stages (stage 4 disease). Now, there are certain neoplasms arising from bone marrow. They are myeloid or lymphoid leukemias.
They are most of the time present in peripheral blood. In addition, leukemia and lymphoma are not merely the presence of certain types of abnormal cells. It is a whole package comprising anemia, leukopenia or leukocytosis, high ESR, thrombocytopenia, unexplained fever, weight loss, arthralgias, myalgias, etc. These are diagnosed using FNAC (fine needle aspiration cytology), bone marrow biopsy, immunohistochemistry, flow cytometry, radiological surveying, etc. These are treated with chemotherapies selected according to the type of cells involved in lesions.
I hope this helps.
Please follow up if you have any doubts.
Thank you.
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Answered byDr. Mubashir Razzaq Khan
Medically reviewed byDr. Chithranjali Ravichandran
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