Is irregular period a common entity in breast cancer patient under chemotherapy?

Hello,

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Loss of ovarian function can happen temporarily or permanently depending on the dosage of the chemotherapy. This happens due to the damage to the immature ovarian follicles containing the immature eggs by the chemotherapeutic agents. So the chances of resumption depend on the ovarian reserve left undamaged. So usually post chemotherapy, a woman may resume her cycles anywhere from a few months to more than a year. Some women may even develop premature ovarian failure. As per your query, irregular cycles are quite common post-chemotherapy once the periods are resumed. But I need to know one more important thing that is the hormone receptor status of the biopsy and whether your wife is on any medication called Tamoxifen. If she is on such medication, then bleeding needs to be monitored by an ultrasound scan to look for the uterine lining thickness.

I hope this helps.