Q. My doctor reduced my Lithium dosage due to the creatinine levels. Why?
Hello doctor,
I have been taking Lithium XR 400 mg twice a day and Valprol CR 300 mg twice a day for the last 19 years. I am also taking Geminor M1 once a day since the last two years. My local doctor checks regularly for my creatinine level and lithium level. My last report of creatinine was 1.36 mg/dL and lithium was 0.48 mmol/L. Now, my local doctor said it is too risky and reduced lithium dosage to 200 mg twice a day. I have no pressure or any other symptoms. But, I am worried what is going on.
Hello,
Welcome to icliniq.com.
I went through your post.
- The normal range of lithium 12 hours after the last dose is 0.6 to 1.2. Your level is 0.48, which is already low. So, instead of decreasing the dose, you may need to increase it to maintain it at a therapeutic level. Consult your specialist doctor, discuss with him or her and start taking the medicines with their consent.
- Your creatinine of 1.36 is not that bad at 50 years of age. So, that is something you need not worry about. There is no risk with lithium at this creatinine. So, take a proper dose.
Regards.
For more information consult an internal medicine physician online --> https://icliniq.com./ask-a-doctor-online/internal-medicine-physician
Thank you doctor,
Perfect answer. But, I am confused that if I save my depression, then I will lose my kidney function and if I save my kidney, then I depression gets worse.
Hello,
Welcome back to icliniq.com.
- Lithium can cause acute as well as chronic nephropathy. But, you need to do glomerular filtration rate (GFR), possibly a DTPA scan and a repeat KFT (kidney function test) after six weeks. If it is normal or same, then you can continue. Otherwise, if it rises, then you may have to stop and increase the Valprol dose.
Regards.
For more information consult an internal medicine physician online --> https://icliniq.com./ask-a-doctor-online/internal-medicine-physician
Thank you doctor,
Your answer is totally perfect because my local doctor also told that if the next report if creatinine is increased, we will increase the Valprol dose.
Hello,
Welcome back to icliniq.com.
- Yes, that is what the guidelines for modifying treatment say so.
- If possible, do a DTPA scan to see how well the kidneys are functioning at present.
Regards.
For more information consult an internal medicine physician online--->https://icliniq.com./ask-a-doctor-online/internal-medicine-physician
Thank you doctor,
Will my mood be covered by Valprol at this dose without any damage to any organs or the kidneys? What is the perfect diet for me?
Hello,
Welcome back to icliniq.com.
- Valproic acid does not have any significant side effects related to kidneys and the dose of Valproic acid can be increased to 20 mg per kg per day.
- A diet rich in fresh fruits and vegetables alone, with regular exercises, will improve the mood as well as keep the kidney functions normal.
Regards.
For more information consult an internal medicine physician online --> https://icliniq.com./ask-a-doctor-online/internal-medicine-physician
Was this answer helpful?
|Same symptoms doesn’t mean you have the same problem. Consult a doctor now!
Related Questions:
Can you list the drugs incompatible with Quetiapine and Lamotrigine?
.. for Lamotrigine following drug interactions need to be considered as important. Valproate increases plasma level of Lamotrigine, hence dose need to be decreased if given with Valproate. Also there are increased chances of rash if given with Valpro... Read full
My creatinine is 3.05 mg/dL. How bad is it?.. understand, you are having hypertension for past 15 years, apparently under control at present. Many a time, hypertension can remain undetected, without symptoms for long. So we may not know the exact duration of the disease in many patients. You ... Read full
Are there any liver supplements I can take while on Risperdal and Depakote?In my endoscopy result it is said that ... pancreatic islets rests in antrum .. what does it signify ? Read full
Also Read Answers From:
Comprehensive Medical Second Opinion.Submit your Case
Also Read
Coronavirus Variant Arcturus: | Omicron XBB.1.16 Variant
Arcturus is an emerging variant of the Omicron virus that causes various symptoms and spreads rapidly across the world. ... Read more»
Adrenaline Rush - Symptoms, Causes, Effects, and How to Control
Adrenaline is a hormone responsible for fight or flight response. It is also a neurotransmitter and medicine. It is also... Read more»
Fatty Liver - Types, Symptoms, Stages, and Treatment
The liver is the largest gland in the body. Its primary function is to process the food and drinks we consume. and filte... Read more»
Ask your health query to a doctor online?
Ask an Internal Medicine Physician Now* guaranteed answer within 4 hours.
