My wife has been advised bone marrow test after she developed an allergy during the blood transfusion for low hemoglobin. Please help.

Q. Does a bone marrow test help in detecting the cause of low hemoglobin?

Answered by
Dr. Goswami Parth Rajendragiri
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on May 27, 2023 and last reviewed on: Aug 10, 2023

Hello doctor,

My wife aged 36 with low hemoglobin got her hemoglobin and platelet increased. But after two months, she had vomiting and developed jaundice, and the hemoglobin got reduced again. The doctors advised two bottles of blood transfusion, but after 75 % of the blood was transfused, she got allergic for two days. Her hemoglobin is now 6.5 to 7 g/dL, and the doctors are now asking her to take a bone marrow test as they feel that the blood is dissolving. What should I do doctor?



Welcome to

I read your query and can understand your concern. I have noted that your wife's hemoglobin level is not increasing with iron treatment and decreasing for two months according to the history provided. Moreover, she had suffered from jaundice as well. So, I suggest you rule out hemolytic anemia by peripheral smear examination, reticulocyte count estimation, serum LDH estimation, and further reports accordingly. You can consult a hematologist for getting evaluated further. If no cause is identified then a bone marrow-like invasive study should be done. Hope I have answered your question. Let me know if I can assist you further. Thanks and take care.

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