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Q. Had Medroxyprogesterone after a negative scan and now I am getting positive UPT test. How?

Answered by
Dr. R Balakrishnan Menon
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Dec 02, 2018

Hello doctor,

I am 26 years old. I went to my PCP for a pregnancy test and it was positive. Had an ultrasound a few days later and the technician said he did not see pregnancy in my uterus so he performed a transvaginal ultrasound to see if I was pregnant in my uterus but I was not. I took a pregnancy test there it was negative. I went back to my PCP 10 days later for blood work to see if my hormone levels are going up or down. Two days later she told me I did not need to come back in for a second bloodwork because I definitely was not pregnant. So she prescribed me Medroxyprogesterone 5 mg for 10 days to restart my cycle because I still have not. I am on day 7 and I took a pregnancy test yesterday night and it gave a visible faint line positive result. So I tested again this morning and I still have a positive result. Could this be because of the Medroxyprogesterone?

Dr. R Balakrishnan Menon

Infertility Obstetrics And Gynaecology


Welcome to

How are you doing? You are about 14 weeks gestation, based on your last menstrual period. At this size, the embryo is easily visible. The blood test will also have high hormonal levels. Pregnancy hormone detected by scan and urine is serum beta hCG. If the fetus is healthy, the levels of this hormone increases exponentially. So if it is 2 Iunits today, in 48 hours it will be 4 IU, and so on. So by 14 weeks, the levels should be very high and easily seen on the scan. Mostly doctor noted a very low level of this hormone. It takes a few weeks for this level to fall to below detectable levels. If you want to still confirm the health of the baby, ask the doctor for the beta hCG result. After 48 hours of the test, check the same beta hCG. If the embryo is healthy, the level of hCG will double. If the baby is unhealthy, this level will fall or rise, will be less than double. So, Medroxyprogestrone acetate will not cause pregnancy hormone reaction, so this hormone is not causing pregnancy hormones. If your doctor feels that levels are very low. I would advise you to wait for 10 to 14 days. You will have periods, if the baby is not there.

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