Q. What is the treatment option for Parkinson's disease other than Levodopa?

Hi,

Welcome to icliniq.com.

I want to assure you that do not worry as everything is going to be fine soon. I have thoroughly gone through your case and can well understand your genuine concerns.

First thing is unless the diagnosis is made by an expert physician, the resembling symptoms do not mean straight that you have Parkinson's disease.
There are many other drugs that are to be used as an adjunct to the Levodopa and that show a good result in many patients. Such as Levodopa with Carbidopa (a peripheral decarboxylase inhibitor) is a good combination.
Also we have Ach-Acetylcholinesterase inhibitors, NMDA (N-Methyl-D-Aspartate) antagonists, COMT (catechol-O-methyl transferase) inhibitors, MAO-B (Monoamine oxidase-B) inhibitors, anticholinergics, etc.
Your symptoms can also be due to other conditions such as liver disease (hepatitis and cirrhosis), anemia, fluid and electrolyte imbalance, thyroid disease and blood pressure issues.

Please answer the below mentioned questions for better diagnosis and treatment.
1. What is your age, gender, height, weight and waist circumference?
2. What is your manganese level? If you have the laboratory reports kindly upload.
3. Have you checked your pulse rate, blood pressure and blood sugar level recently?
4. Please send me all laboratory reports, MRI, CT, radiographs, etc., relevant to your query.

Investigations you need includes,
1. Comprehensive metabolic panel.
2. Liver viral markers for hepatitis B and C.
3. Thyroid profile.

1. Liver disease.
2. Anemia.
3. Thyroid disease.
4. Diabetes.

Treatment will be decided according to your laboratory reports. As there are many possibilities, we have to proceed with care.

Hi,

Welcome back to icliniq.com.

I want to assure you that do not worry as everything is going to be fine soon. I have thoroughly gone through your case and can well understand your genuine concerns.

Your main issue is dyslipidemia (deranged lipid profile). Over the last 4 years, in all laboratory reports you have high bad cholesterol and low good cholesterol.

1. Whenever a patient presents with complaint as you have and the lipid profile too the same as yours then I usually prescribe him first of all to follow diet and lifestyle modification.
In majority of patients, it works very well and gets lipid under control.
2. Very few number of patients need some medication for long-term like Fenofibrate or Pravastatin.
3. You need to lose some weight with diet control and exercise. All the symptoms you have are consistent with the diagnosis.
4. Take Sea-Mega capsules and fatty fish in food (for example herring fish).
5. No fat and carbohydrates in excess and say no to fried foods, fast food, energy drinks and beverages.
6. Avoid red meat, chicken, alcohol and cigarette.
7. Avoid excess salt and sugar.
8. Take plenty of water.
9. Start proper physical activity and make it a habit. It will help you get HDL up, LDL and triglycerides low.

After some weeks come back to me with a fresh comprehensive metabolic panel including fasting lipid profile to see how you doing and I will be able to decide if you need medications to lower the levels.

Dr. Muhammad M. Hanif Md.

Cardiology

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