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I have irregular periods even after taking PCOS/PMOS medicines for four months. Why?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My recent USG showed bilateral polycystic ovaries. Both the ovaries are mildly enlarged with multiple tiny cysts peripherally arranged. I have irregular periods for ten years. And three years ago, I showed the doctor for these tiny cysts. I took Metformin and Normen according to her advice. But I stopped it after four months. Should I continue the medication again, and for how long? Please note my prolactin and TSH is at a normal level. Do I need any further investigation? Kindly guide me.

Hello,

Welcome to icliniq.com.

I understand your concern. PCOS (polycystic ovary syndrome)/PMOS (polyendocrine metabolic ovarian syndrome) is a disorder that presents throughout life and is easily managed by medication and lifestyle changes. PCOS/PMOS makes it difficult to conceive and may present with menstrual problems. This can also lead to other complaints like weight gain, acne, hair loss, voice change, facial hair, diabetes, etc. Hence it is a necessity you take the right step. Metformin will help reduce insulin resistance and help in weight loss, and prevents diabetes. Normen (Norethindrone Acetate) is progesterone that your doctor has prescribed for regular periods. Though these will help, it is important to make many lifestyle changes and continue newer medication. I suggest you start medications again (cyclic oral contraceptives) with Metformin, PCOS diet, and exercise after consultation with a gynecologist.

I hope this was helpful.

Medically reviewed byDr. Sushrutha M.

Published At August 10, 2021
Reviewed AtMay 27, 2026

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