Q. My PSA level is high. Should I get a biopsy?

Answered by
Dr. Aman Gupta
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Nov 01, 2016 and last reviewed on: Oct 12, 2020

Hi doctor,

I am 62 years old. I have severe pain while urinating and having frequent urination at night. My PSA 62.32, prostate 78 g, RUV 142 mL. Should I get a biopsy?



Welcome to icliniq.com.

  • I hope your doctor has examined you physically. If there is a doubt of any tumor on prostate examination, then a biopsy should be done.
  • If there is any history of a recent proven urinary tract infection in the last few days, then PSA (prostate-specific antigen) may be falsely elevated.
  • In this situation, an antibiotic like Levofloxacin 500 once a day is given for two weeks and PSA repeated. If it becomes normal, then a biopsy can be omitted. Otherwise, 12 core TRUS-guided prostate biopsy must be done (transrectal ultrasound guided biopsy).
  • If it is benign, then go for a TURP (transurethral resection of the prostate) or laser prostatectomy as your residual urine is high. Medicines can be tried if your physician feels so.
  • If it comes out to be malignant, then some further tests to ascertain the stage need to be done. It may include bone scan, MRI pelvis or PSMA scan (prostate-specific membrane antigen) and the treatment differs depending on the stage.

For further information consult a urologist online --> https://www.icliniq.com/ask-a-doctor-online/urologist

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