Q. I want to go off antidepressants but have trouble sleeping. What can I do?

Answered by
Dr. Vishal Anilkumar Gandhi
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Feb 07, 2018 and last reviewed on: Oct 27, 2022

Hello doctor,

I am 22 years old. I have been on the following antidepressants for two years. Morning: Modapex 50 one pill, Depakene, Lamotrigine 25 mg one pill. Night: Clozapex 25 mg half a pill, Mirtimash 30 g half a pill, Depakine Chrono 500 mg one pill, and Anafranil 75 mg half a pill.

I used to take more but I stopped them over the past two years. For example, I used to take double the mentioned dose about nine months ago. I recovered from depression a couple of months ago. I started detoxing but with my doctor, the process was going way too slow and I have gained 45 kilograms over the past two years (25 in the past two months alone!) my muscles, my bones, and my joints started to hurt really bad because of my weight. Nothing works. I go to the gym every day, I workout but still I eat way too much because of the drugs and I cannot control it. My doctor does not want me to stop despite every hardship that I face and even refuses to decrease half a pill from the prescription. However, three weeks ago, I decided to cut all medications once and for all. I lost 7 kilograms, I stopped eating too much and just by cutting down the drugs I saved not less than 1800 calories per day. I started going to the gym more regularly. But here is the problem.

Clozapex 25 and Mirtimash make me sleep and without them, I cannot sleep. No kidding, I have not slept in the past three weeks more than a maximum of 70 hours. Even those 70 hours, they are full of nightmares and I usually wake up after two hours with my mind confused and afraid and I cannot sleep back. I want to sleep. My eyes grew tired because I have been opening them for way too long. I do not want to give in and get back to the drugs because I am sick of them and I have had enough. I am not going back but I also want to sleep. Just a single continuous eight hours of sleep without any nightmares. I usually get nightmares that are very weird. I do not even know how to describe them. Mathematical problems and complicated solutions that are presented to me (in my sleep) and I keep thinking about them until my head hurts and I wake up freaked out. Please tell me what to do. I thought that after three weeks it would get easier but it is not getting easier. I have no side effects at all from any of the drugs only the disturbance of sleep. Some of them were written on them that if you would stop them suddenly you would risk getting seizures but nothing happened thankfully. I am not even depressed or sad I am just irritated and sad about the sleeping problem.

Kindly help.



Welcome to

Because of stopping the medication you have a problem with sleep. You should try some sleep medication for a short time and then taper it.

I suggest tablet Diazepam 5 mg before sleep. It is Benzodiazepine group drug and long duration, but it is addictive. So, you must taper it within four to six weeks. Or you can try tablet Zolpidem 5 mg before sleep. It is a good medication but it is not so effective like Benzodiazepine. Zolpidem does not get you addicted. Consult your specialist doctor, discuss with him or her and start taking the medicines with their consent. Or you can try tablet Melatonin which is a normal nonprescription medication. You can get it online or over the counter.

The non-pharmacological ways to sleep better are:

  1. Avoid electronic gadgets like mobile, laptop, and TV from at least one hour before sleep.
  2. Fix your sleeping time and wake up time.
  3. Do not take stimulants like coffee, chocolate, or tea before sleep.
  4. Have dinner at least three hours before sleep.
  5. Do not carry your work to the bed. Do not use the bed for anything except sleeping.
  6. Do some yoga or relaxation techniques.
  7. If possible, drink lukewarm milk before sleep.
  8. Keep the room dark and maintain proper temperature and ambiance for good sleep.

Hope this will help you.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
Why is my son put on Paroxetine in spite of having bad withdrawals previously?

He has been on and off antidepressants since he was 16 years old due to high anxiety issues ... Paxil (Paroxetine) and Gabapentine (Gabapentin) are used in anxiety or depression ...   Read full

Do antidepressants cause low sex drive?

Do you have any psychological issues like depression, anxiety or even simple stress ... I am suffering with anxiety and depression and take numerous medications such as Prozac, Klonopin, Trazodon...   Read full

Does Seroquel extend the time of my derealization last longer?

Seroquel is Quetiapine and is an antipsychotic drug, but the drug is also used in mood disorders like bipolar disorder or resistant depression ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Coronavirus Variant Arcturus: | Omicron XBB.1.16 Variant
Arcturus is an emerging variant of the Omicron virus that causes various symptoms and spreads rapidly across the world. ...  Read more»
Adrenaline Rush - Symptoms, Causes, Effects, and How to Control
Adrenaline is a hormone responsible for fight or flight response. It is also a neurotransmitter and medicine. It is also...  Read more»
Fatty Liver - Types, Symptoms, Stages, and Treatment
The liver is the largest gland in the body. Its primary function is to process the food and drinks we consume. and filte...  Read more»

Ask your health query to a doctor online?

Ask a Psychiatrist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.