Q. Can Aleve and Goody's powder cause stomach upset?

Answered by
Dr. Jeremy David O' Kennedy
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Apr 30, 2017 and last reviewed on: Feb 01, 2023

Hi doctor,

I recently had a migraine, so I took two tablets of Aleve. It did not work, so I took Goody's powder, but the pain was still there, so I took another one. The migraine pain has gone, but my stomach seems to be upset.



Welcome to

Sorry to hear about your headache.

  • Aleve (Naproxen) and Goody's powder (combination of Aspirin, Acetaminophen, and Caffeine) both contain NSAIDs (non-steroidal anti-inflammatory drugs) like Aspirin, Ibuprofen, Naproxen, Piroxicam, Diclofenac, etc.
  • Although NSAIDs are very effective at treating certain kinds of inflammation (especially musculoskeletal), some of them block an enzyme pathway responsible for producing the protective mucous which lines the stomach and intestines. This leads to erosive gastritis or even stomach or duodenal ulcers (peptic ulcers) when used for too long, in an empty stomach, or in susceptible individuals.
  • The caffeine content in Goody's powder is a gastric irritant on its own, making it a very dangerous combination and not a drug looked upon favorably by physicians. It sounds like your symptoms were likely caused by the side effects of the NSAIDs you took for your headache.
  • I would recommend stopping all NSAIDs that you might be taking and starting a PPI (proton-pump inhibitor) like Omeprazole. It can be taken for 4 to 6 weeks, to help restore the integrity of the stomach. If your symptoms worsen not withstanding above advice, consult a trusted physician to exclude other causes.
  • As a side note, the Triptans are medication specifically formulated for migraine treatment and drugs like Rizatriptan are highly effective and will not damage the gastric lining.

For more information consult an internal medicine physician online -->

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
I am suffering from ankylosing spondylitis. Kindly suggest new medications.

Hello, Welcome back to icliniq ... Once your pain is controlled, you can try to reduce the dose to alternate days or even lesser depending on your pain ...   Read full

I am having burning pain in my stomach with nausea. Is it due to caffeine?

It is much worse with little sleep or food or stress or anxiety ...   Read full

Taking Pantoprazole for GERD. Is any drug interactions between Pantoprazole and Voltaren?

I just took 50 mg Voltaren for a bad back and I am worried sick ... In fact, anyone who takes painkillers like Diclofenac has to take Pantoprazole to prevent Diclofenac-induced gastritis ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Coronavirus Variant Arcturus: | Omicron XBB.1.16 Variant
Arcturus is an emerging variant of the Omicron virus that causes various symptoms and spreads rapidly across the world. ...  Read more»
Adrenaline Rush - Symptoms, Causes, Effects, and How to Control
Adrenaline is a hormone responsible for fight or flight response. It is also a neurotransmitter and medicine. It is also...  Read more»
Fatty Liver - Types, Symptoms, Stages, and Treatment
The liver is the largest gland in the body. Its primary function is to process the food and drinks we consume. and filte...  Read more»

Ask your health query to a doctor online?

Ask an Internal Medicine Physician Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.